ArticleArchives of osteoporosis2021
Cortical bone thickness predicts the quantitative bone mineral density of the proximal humerus.
Article in Archives of osteoporosis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Measurement of Proximal Humeral Cortical Bone Thickness to Predict Intraoperative Anchor Stability in Arthroscopic Rotator Cuff Repair: A Retrospective Case-Control Study of a Reliable Radiographic Marker for Surgical Planning.Orthopaedic journal of sports medicine · 2026Article
- Lower average cortical bone thickness predicts cemented fixation in short-stem reverse shoulder arthroplasty.Journal of orthopaedic surgery and research · 2026Article
- No impact of osteoporosis on stemless reverse shoulder arthroplasty stability.International orthopaedics · 2026Article
- A mouse model for hemoglobin SC disease recapitulates characteristic human pathologies.Blood advances · 2025Article
- Quantitative Computed Tomography-Based Analysis of Bone Structure in the Surgical Neck of the Humerus during Aging in Men.Calcified tissue international · 2025Article
- Surgical Management of Osteoporotic Fractures: Humerus Shaft Fractures.Indian journal of orthopaedics · 2025Review
- Preventing reduction loss following proximal humerus fractures after locking compression plate fixation: a new clinical prediction model.BMC musculoskeletal disorders · 2025Article
- Incidence and predictors of dorsal comminution in older adults with low-energy distal radius fracture.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Article
- Age-related Differences in Volumetric Bone Mineral Density, Structure, and Bone Strength of Surgical Neck of Humerus in Postmenopausal Women.Orthopaedic surgery · 2024Article
- Advanced porous hip implants: A comprehensive review.Heliyon · 2024Review
- Article
- Hounsfield units predicts the occurrence but not the patterns of proximal humerus fracture in the elderly patients.BMC musculoskeletal disorders · 2023Article
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6 authors.
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Abstract
Cortical thickness determined at the humerus can serve as an easy and reliable screening tool to predict the local bone status when quantitative bone mineral density (BMD) measurements are not available. It can therefore serve as a rapid screening tool in fragility fractures to identify patients requiring further diagnostic or osteoporosis treatment.
introductionQuantitative bone mineral density (BMD) of the humerus is difficult to determine but relevant for osteoporosis and fracture treatment. Dual-energy X-ray absorptiometry (DXA) of the femur and lumbar spine overestimates the humeral BMD and is not ubiquitously available. Therefore, this study evaluated whether the cortical bone thickness (CBT) of the humerus or DXA of the forearm is able to predict humeral BMD.
methodsHumeral BMD of 54 upper cadaver extremities (22 pairs, 10 single) (19-90 years) was determined by high-resolution peripheral-quantitative-computed-tomography (HR-pQCT) (volumetric BMD (vBMD)) and DXA (areal BMD (aBMD)) of the proximal humerus and distal forearm. Average and gauge cortical bone thickness (CBTavg/ CBTg) of the humeral diaphysis was determined from standard radiographs (XR) and computed-tomography (CT) and compared to the humeral BMD. Pearson (r) and intraclass-correlation-coefficients (ICC) were used to compare results and rater-reliability.
resultsCBTavg from XR strongly correlated with the humeral BMD (r = 0.78 aBMD (DXA) and r = 0.64 vBMD (HR-pQCT) (p < 0.0001)). The CBTg revealed a weaker correlation (r = 0.57 aBMD and r = 0.43 vBMD). CBT derived from XR strongly correlated to those from the CT (r = 0.82-0.90) and showed an excellent intra- and inter-rater correlation (ICC 0.79-0.92). Distal forearm aBMD correlated well with the humeral aBMD (DXA) (r = 0.77) and paired specimens highly correlated to the contralateral side (humerus r = 0.89, radius r = 0.97).
conclusionsThe CBTavg can reliably be determined from standard radiographs and allows a good prediction of quantitative humeral bone mineral density (aBMD or vBMD) if measurements are not available. Furthermore, the distal forearm or the contralateral humerus can serve as a side to estimate the BMD if the ipsilateral side is impaired.
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