ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Assessing the thrombosis risk of peripherally inserted central catheters in cancer patients using Caprini risk assessment model: a prospective cohort study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- Clinical factors of PICC-RVT in cancer patients: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Pooled it
- Systematic review of venous thromboembolism risk categories derived from Caprini score.Journal of vascular surgery. Venous and lymphatic disorders · 2022Pooled it
- Development and preliminary validation of a PICC-related venous thrombosis risk prediction model for cancer patients: A systematic review and meta-analysis predominantly based on Chinese populations.Asia-Pacific journal of oncology nursing · 2026Review
- Association of triglyceride-glucose related indices with the incidence of venous thromboembolism: a nationwide prospective cohort study based on the UK Biobank.BMC cardiovascular disorders · 2026Article
- Risk factors for catheter-related thrombosis in cancer patients: a systematic review.Frontiers in cardiovascular medicine · 2026Review
- A nomogram predicting venous thromboembolism risk in primary liver cancer patients.Journal of thrombosis and thrombolysis · 2025Article
- Development and Internal Validation of a Predictive Model for Deep Venous Thrombosis Following Colpocleisis in Elderly Patients with Pelvic Organ Prolapse.Risk management and healthcare policy · 2025Article
- Central venous access device terminologies, complications, and reason for removal in oncology: a scoping review.BMC cancer · 2024Article
- Application of the Caprini risk model in preventing deep venous thrombosis formation in patients with nephrotic syndrome.American journal of translational research · 2024Article
- Biomarkers Associated with Thrombosis in Patients with Peripherally Inserted Central Catheter: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- A clinical study of peripherally inserted central catheter-related venous thromboembolism in patients with hematological malignancies.Scientific reports · 2022Article
- A model to assess the risk of peripherally inserted central venous catheter-related thrombosis in patients with breast cancer: a retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
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Authors and funding
8 authors at 1 institution in 1 country.
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Abstract
purposeThere was no optimal risk assessment tool to stratify the risk of peripherally inserted central catheter-related venous thromboembolism (PICC-RVT) in cancer patients. We currently use the Caprini risk assessment model for thrombotic risk assessment, but no evidence exists on the effectiveness of Caprini in such patients. This study was to assess the validity of the Caprini in Chinese cancer patients with PICCs.
methodsWe conducted a prospective study of 468 participants. Following calculating the Caprini score, color Doppler ultrasonography was performed every 7 days for 3 weeks to confirm PICC-RVT.
resultsThere was a correlation between PICC-RVT and the Caprini score. Compared with scores of 5, the risk was 2.089-fold greater (95% CI 1.165-3.743, P = 0.012) in patients with a score of 6 and 7, and 7.156-fold greater (95% CI 3.157-16.217, P < 0.001) in patients with scores ≥8. The area under the receiver-operating characteristic curve was 0.636 (95% CI 0.590-0.680; P < 0.001). 6 was the best cutoff point for Caprini, with a sensitivity of 0.76 and a specificity of 0.44.
conclusionsThe Caprini can be used for high-risk screening of the PICC-RVT in cancer patients, and classification of the highest risk level using a score of 6 can be more clinically significant compared to 5 as recommended. The results provide evidence for the practitioner's early use of the Caprini to assess the thrombotic risk in patients with PICCs and take timely prevention measures. But pharmacological prevention should be considered seriously for its low specificity.
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