Evidence map›Paper›PMID 33594341›Full record

ArticleTobacco regulatory science2018

Multi-year Study of PAHs in Mainstream Cigarette Smoke.

Bryan A Hearn, Yan S Ding, Clifford H Watson, Tricia L Johnson, Getie Zewdie, Jeannie H Jeong-Im, Matthew J Walters, Matthew R Holman, C George Rochester

Open access · diamondAbstract read
In one paragraph

Article in Tobacco regulatory science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Carcinogenic components of tobacco and tobacco smoke: A 2022 update.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Bryan A HearnBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Yan S DingBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Clifford H WatsonBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Tricia L JohnsonBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Getie ZewdieBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Jeannie H Jeong-ImBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Matthew J WaltersBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
Matthew R HolmanBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
C George RochesterBryan A. Hearn, Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Yan S. Ding, Health Scientist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Clifford H. Watson, Lead Research Chemist, National Center for Environmental Health, US Centers for Disease Control and Prevention, Atlanta, GA. Tricia L. Johnson, Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Getie Zewdie, Mathematical Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Jeannie H. Jeong-Im, Review Chemist, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew J. Walters, Deputy Division Director, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. Matthew R. Holman, Director, Office of Science, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD. C. George Rochester, Chief Statistician, Center for Tobacco Products, US Food and Drug Administration, Silver Spring, MD.
National Center for Environmental Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesCorrelations are made between mainstream cigarette smoke deliveries of individual PAHs over multiple years. Average overall PAH deliveries in mainstream cigarette smoke by study year, mentholation, ring size, and manufacturer are compared.

methodsMainstream smoke deliveries were determined by GC/MS for 14 polycyclic aromatic hydrocarbons (PAHs) from selected cigarettes on the US market in 2002, 2004, 2007, and 2011. The mainstream smoke PAH emissions were measured under international standardization organization (ISO) smoking conditions. Pearson product-moment correlation was used to examine the linear relationship among the PAHs over multiple years.

resultsA number of the PAH analytes were statistically highly correlated with each other. The overall average for mainstream smoke deliveries of PAHs did not change significantly between study years. Similar levels in average PAH deliveries were seen for mentholated and non-mentholated cigarettes.

conclusionsThe strong correlations between PAH compounds over multiple years show that a limited set of PAHs can predict deliveries of others with confidence over multiple years. A more limited panel of analytes may be considered when designing studies involving PAH measurements in mainstream smoke.

Indexed as

mainstream cigarette smokePAH correlationsPAHspolycyclic aromatic hydrocarbons

Identifiers

PMID33594341
PMCPMC7884091
OpenAlexW2803857817

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.