Evidence map›Paper›PMID 33594327›Full record

ArticleAmerican journal of translational research2021

The sodium/D-dimer ratio predicts the effect of first-line chemotherapy and prognosis in patients with advanced gastric cancer.

Liqun Zhang, Guilin Yu, Zhuo Wang, Fang Li, Guohua Zhao, Dan Zhao

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Liqun ZhangDepartment of Medical Oncology, Shenyang Fifth People Hospital Tiexi District, Shenyang 110020, Liaoning Province, China.
Guilin YuDepartment of General Surgery, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Zhuo WangDepartment of Medical Oncology, Liaohua Hospital Hongwei District, Liaoyang 111003, Liaoning Province, China.
Fang LiDepartment of Hepatobiliary Surgery, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Guohua ZhaoDepartment of General Surgery, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Dan ZhaoDepartment of Medical Imaging, Liaoning Cancer Hospital & Institute, Cancer Hospital of China Medical University No. 44 Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China.
Liaoning Cancer Hospital & Institute · CNShenyang Fifth People Hospital · CNThird People 's Hospital of Liaoyang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer (GC) is one of the most common cancers worldwide. The survival time of patients with advanced gastric cancer (AGC) is shortened. We evaluated the role of the sodium/fibrinogen ratio (SFR) and sodium/D-dimer ratio (SDR) in predicting the first-line chemotherapy response, progression-free survival (PFS), and overall survival (OS) of patients with AGC.

methodsA total of 304 patients with AGC were retrospectively reviewed. SDR only was selected as a potential prognostic marker for the subsequent studies in this study. Based on the cut-off value of the SDR, the patients were divided into high-SDR and low-SDR groups and investigated for their clinicopathological features, first-line chemotherapy effects and clinical outcomes.

resultsThe cut-off value based on the SDR was 282.22, and the patients were divided into low-SDR (SDR ≤ 282.22) and high-SDR (SDR > 282.22) groups. The disease control rate was higher in the high-SDR group than in the low-SDR group (91.1% vs. 82.3%;

conclusionsThis study suggests that the SDR may serve as a prognostic indicator for chemotherapy outcome, PFS and OS for patients with AGC receiving first-line chemotherapy.

Indexed as

first-line chemotherapygastric canceroverall survivalprognosisprogression-free survivalSodium/D-dimer ratio

Identifiers

PMID33594327
PMCPMC7868830
OpenAlexW3132553692

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.