Evidence map›Paper›PMID 33594196›Full record

ArticleScientific reports2021

Biochemical aspects of seeds from Cannabis sativa L. plants grown in a mountain environment.

Chiara Cattaneo, Annalisa Givonetti, Valeria Leoni, Nicoletta Guerrieri, Marcello Manfredi, Annamaria Giorgi, Maria Cavaletto

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Nutrients and Bioactive Compounds fromInternational journal of molecular sciences · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Chiara CattaneoDipartimento di Scienze e Innovazione Tecnologica-DiSIT, Università del Piemonte Orientale, 13100, Vercelli, Italy. chiara.cattaneo@uniupo.it.
Annalisa GivonettiDipartimento di Scienze e Innovazione Tecnologica-DiSIT, Università del Piemonte Orientale, 13100, Vercelli, Italy.
Valeria LeoniCentre of Applied Studies for the Sustainable Management and Protection of Mountain Areas (CRC Ge.S.Di.Mont.), University of Milan, Via Morino 8, 25048, Edolo, (BS), Italy.
Nicoletta GuerrieriWater Research Institute-National Research Council (IRSA-CNR), Verbania, Italy.
Marcello ManfrediCentro di Ricerca Traslazionale sulle Malattie Autoimmuni e Allergiche- CAAD, Università del Piemonte Orientale, 28100, Novara, Italy.
Annamaria GiorgiCentre of Applied Studies for the Sustainable Management and Protection of Mountain Areas (CRC Ge.S.Di.Mont.), University of Milan, Via Morino 8, 25048, Edolo, (BS), Italy.
Maria CavalettoDipartimento di Scienze e Innovazione Tecnologica-DiSIT, Università del Piemonte Orientale, 13100, Vercelli, Italy.
Università degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Milan · ITWater Research Institute · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabis sativa L. (hemp) is a versatile plant which can adapt to various environmental conditions. Hempseeds provide high quality lipids, mainly represented by polyunsaturated acids, and highly digestible proteins rich of essential aminoacids. Hempseed composition can vary according to plant genotype, but other factors such as agronomic and climatic conditions can affect the presence of nutraceutic compounds. In this research, seeds from two cultivars of C. sativa (Futura 75 and Finola) grown in a mountain environment of the Italian Alps were analyzed. The main purpose of this study was to investigate changes in the protein profile of seeds obtained from such environments, using two methods (sequential and total proteins) for protein extraction and two analytical approaches SDS-PAGE and 2D-gel electrophoresis, followed by protein identification by mass spectrometry. The fatty acids profile and carotenoids content were also analysed. Mountain environments mainly affected fatty acid and protein profiles of Finola seeds. These changes were not predictable by the sole comparison of certified seeds from Futura 75 and Finola cultivars. The fatty acid profile confirmed a high PUFA content in both cultivars from mountain area, while protein analysis revealed a decrease in the protein content of Finola seeds from the experimental fields.

Indexed as

AltitudeCannabisCarotenoidsChlorophyllEuropean Alpine RegionFatty AcidsGene-Environment InteractionItalyPlant ProteinsSeedsCarotenoidsChlorophyllFatty AcidsPlant Proteins

Identifiers

PMID33594196
PMCPMC7887209
OpenAlexW3130731538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.