Evidence map›Paper›PMID 33594159›Full record

ArticleScientific reports2021

A deep learning integrated radiomics model for identification of coronavirus disease 2019 using computed tomography.

Xiaoguo Zhang, Dawei Wang, Jiang Shao, Song Tian, Weixiong Tan, Yan Ma, Qingnan Xu, Xiaoman Ma, Dasheng Li, Jun Chai and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Automatic identification of pavement cracks in public roads using an optimized deep convolutional neural network model.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2023
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  15. Detection and Prevention of Virus Infection.Advances in experimental medicine and biology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiaoguo Zhang *Department of Respiratory Medicine, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, Shandong, People's Republic of China.
Dawei Wang *Institute of Advanced Research, Infervision Medical Technology Co., Ltd., 18F, Building E. Yuanyang International Center, Chaoyang District, Beijing, 100025, People's Republic of China.
Jiang ShaoDepartment of Radiology, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, People's Republic of China.ORCID 0000-0001-9153-8006
Song TianInstitute of Advanced Research, Infervision Medical Technology Co., Ltd., 18F, Building E. Yuanyang International Center, Chaoyang District, Beijing, 100025, People's Republic of China.
Weixiong TanInstitute of Advanced Research, Infervision Medical Technology Co., Ltd., 18F, Building E. Yuanyang International Center, Chaoyang District, Beijing, 100025, People's Republic of China.
Yan MaDepartment of Respiratory Medicine, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, Shandong, People's Republic of China.
Qingnan XuDepartment of Respiratory Medicine, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, Shandong, People's Republic of China.
Xiaoman MaDepartment of Respiratory Medicine, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, Shandong, People's Republic of China.
Dasheng LiDepartment of Radiology, Beijing Haidian Section of Peking University Third Hospital (Beijing Haidian Hospital), 29# Zhongguancun Road, Haidian District, Bejing, 100080, People's Republic of China.
Jun ChaiDepartment of Radiology, Inner Mongolia Autonomous Region People's Hospital, 20# Zhaowuda Road, Hohhot, 010017, People's Republic of China.
Dingjun WangDepartment of Radiology, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, 365# Renmin East Road, Wucheng District, Jinhua, 321000, People's Republic of China.
Wenwen LiuDepartment of Radiology, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, People's Republic of China.
Lingbo LinDepartment of Radiology, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, People's Republic of China.
Jiangfen WuInstitute of Advanced Research, Infervision Medical Technology Co., Ltd., 18F, Building E. Yuanyang International Center, Chaoyang District, Beijing, 100025, People's Republic of China.
Chen XiaInstitute of Advanced Research, Infervision Medical Technology Co., Ltd., 18F, Building E. Yuanyang International Center, Chaoyang District, Beijing, 100025, People's Republic of China.
Zhongfa ZhangDepartment of Respiratory Medicine, Jinan Infectious Disease Hospital, Shandong University, 22029# Jing-Shi Road, Jinan, 250021, Shandong, People's Republic of China. zhzflab@163.com.

Funding

Jinan Science and Technology Bureau (Jinan Science & Technology Bureau) 202001003
6 · The paper itself

Abstract

Since its first outbreak, Coronavirus Disease 2019 (COVID-19) has been rapidly spreading worldwide and caused a global pandemic. Rapid and early detection is essential to contain COVID-19. Here, we first developed a deep learning (DL) integrated radiomics model for end-to-end identification of COVID-19 using CT scans and then validated its clinical feasibility. We retrospectively collected CT images of 386 patients (129 with COVID-19 and 257 with other community-acquired pneumonia) from three medical centers to train and externally validate the developed models. A pre-trained DL algorithm was utilized to automatically segment infected lesions (ROIs) on CT images which were used for feature extraction. Five feature selection methods and four machine learning algorithms were utilized to develop radiomics models. Trained with features selected by L1 regularized logistic regression, classifier multi-layer perceptron (MLP) demonstrated the optimal performance with AUC of 0.922 (95% CI 0.856-0.988) and 0.959 (95% CI 0.910-1.000), the same sensitivity of 0.879, and specificity of 0.900 and 0.887 on internal and external testing datasets, which was equivalent to the senior radiologist in a reader study. Additionally, diagnostic time of DL-MLP was more efficient than radiologists (38 s vs 5.15 min). With an adequate performance for identifying COVID-19, DL-MLP may help in screening of suspected cases.

Indexed as

Deep LearningModels, BiologicalTomography, X-Ray ComputedAdultAlgorithmsCOVID-19FemaleHumansMaleMiddle AgedRadiologistsROC CurveSARS-CoV-2

Identifiers

PMID33594159
PMCPMC7886892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.