ArticleScientific reports2021
Digital gene expression analysis of the response to Ralstonia solanacearum between resistant and susceptible tobacco varieties.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 37 citations in OpenAlex.
- Integrated transcriptomic and metabolomic analysis revealed the response of resistant variety Zhonghua 6 to the infection of Ralstonia solanacearum in peanut.BMC plant biology · 2026Article
- Enhanced resistance toFrontiers in plant science · 2026Article
- Key mechanisms of plant-Frontiers in microbiology · 2025Review
- Multi-omics analysis reveals the specific role of biocontrol reagents against tomato bacterial wilt.Frontiers in plant science · 2025Article
- Response and disease resistance evaluation of sorghum seedlings under anthracnose stress.Scientific reports · 2024Article
- Transcriptome sequencing and expression analysis in peanut reveal the potential mechanism response to Ralstonia solanacearum infection.BMC plant biology · 2024Article
- Superiority of native seed core microbiomes in the suppression of bacterial wilt disease.Frontiers in microbiology · 2024Article
- Uncovering the transcriptional responses of tobacco (Nicotiana tabacum L.) roots to Ralstonia solanacearum infection: a comparative study of resistant and susceptible cultivars.BMC plant biology · 2023Article
- Rhizosphere Microbial Community and Metabolites of Susceptible and Resistant Tobacco Cultivars to Bacterial Wilt.Journal of microbiology (Seoul, Korea) · 2023Article
- CmERF5-CmRAP2.3 transcriptional cascade positively regulates waterlogging tolerance in Chrysanthemum morifolium.Plant biotechnology journal · 2023Article
- Biocontrol fungi induced stem-base rot disease resistance ofFrontiers in microbiology · 2023Article
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- Transcriptome analysis reveals differential transcription in tomato (Solanum lycopersicum) following inoculation with Ralstonia solanacearum.Scientific reports · 2022Article
- Global transcriptome and targeted metabolite analyses of roots reveal different defence mechanisms againstFrontiers in plant science · 2022Article
- Identification of Candidate Genes for a Major Quantitative Disease Resistance Locus From Soybean PI 427105B for Resistance toFrontiers in plant science · 2022Article
- Weighted Gene Co-Expression Analysis Network-Based Analysis on the Candidate Pathways and Hub Genes in Eggplant Bacterial Wilt-Resistance: A Plant Research Study.International journal of molecular sciences · 2021Article
- Identification of Novel Quantitative Trait Nucleotides and Candidate Genes for Bacterial Wilt Resistance in Tobacco (Frontiers in plant science · 2021Article
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Authors and funding
7 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Tobacco bacterial wilt (TBW) caused by Ralstonia solanacearum is the most serious soil-borne disease of tobacco. However, molecular mechanism information of R. solanacearum resistance is limited to tobacco, hindering better breeding of resistant tobacco. In this study, the expression profiles of the rootstalks of Yunyan87 (susceptible cultivar) and Fandi3 (resistant cultivar) at different stages after R. solanacearum infection were compared to explore molecular mechanisms of tobacco resistance against the bacterium. Findings from gene-expression profiling indicated that the number of upregulated differentially expressed genes (DEGs) at 3 and 7 days post-inoculation (dpi) increased significantly in the resistant cultivar. WRKY6 and WRKY11 family genes in WRKY transcription factors, ERF5 and ERF15 family genes in ERFs transcription factors, and genes encoding PR5 were significantly upregulated in the resistant cultivar response to the infection. For the first time, WRKY11 and ERF15 were found to be possibly involved in disease-resistance. The Kyoto Encyclopedia of Genes and Genomes analysis demonstrated glutathione metabolism and phenylpropane pathways as primary resistance pathways to R. solanacearum infection. In the resistant cultivar, DEGs encoding CYP450, TCM, CCoAOMT, 4CL, PAL, CCR, CSE, and CADH, involved in the synthesis of plant antitoxins such as flavonoids, stilbenoids, and lignins, enriched in the phenylpropane pathway were upregulated at 3 and 7 dpi. Furthermore, a pot experiment was performed to verify the role of flavonoids in controlling TBW. This study will strongly contribute to a better understanding of molecular interactions between tobacco plants and R. solanacearum.
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