Evidence map›Paper›PMID 33594082›Full record

Observational studyNPJ primary care respiratory medicine2021

Work absence in patients with asthma and/or COPD: a population-based study.

Boudewijn J H Dierick, Bertine M J Flokstra-de Blok, Thys van der Molen, Núria Toledo-Pons, Miguel Román-Rodríguez, Borja G Cosío, Joan B Soriano, Janwillem W H Kocks, Job F M van Boven

Abstract readObservational Study
In one paragraph

Observational study in NPJ primary care respiratory medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Patient-centred outcomes in severe asthma: fatigue, sleep, physical activity and work.European respiratory review : an official journal of the European Respiratory Society · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Boudewijn J H DierickUniversity of Groningen, University Medical Center Groningen, Groningen Institute for Asthma and COPD (GRIAC), Department of General Practice & Elderly Care Medicine, Groningen, The Netherlands. b.j.h.dierick@umcg.nl.
Bertine M J Flokstra-de BlokGeneral Practitioners Research Institute, Groningen, The Netherlands.
Thys van der MolenUniversity of Groningen, University Medical Center Groningen, Groningen Institute for Asthma and COPD (GRIAC), Department of General Practice & Elderly Care Medicine, Groningen, The Netherlands.ORCID 0000-0002-6606-8804
Núria Toledo-PonsDepartment of Respiratory Medicine, Hospital Universitario Son Espases, and CIBERES, Madrid, Spain.
Miguel Román-RodríguezUniversity of Groningen, University Medical Center Groningen, Groningen Institute for Asthma and COPD (GRIAC), Department of General Practice & Elderly Care Medicine, Groningen, The Netherlands.
Borja G CosíoDepartment of Respiratory Medicine, Hospital Universitario Son Espases, and CIBERES, Madrid, Spain.ORCID 0000-0002-6388-8209
Joan B SorianoHospital Universitario de la Princesa, Universidad Autónoma de Madrid, Madrid, Spain.ORCID 0000-0001-9740-2994
Janwillem W H KocksGeneral Practitioners Research Institute, Groningen, The Netherlands.ORCID 0000-0002-2760-0693
Job F M van BovenUniversity of Groningen, University Medical Center Groningen, Groningen Institute for Asthma and COPD (GRIAC), Department of General Practice & Elderly Care Medicine, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) and asthma impact on work productivity, but their population-based burden and clinical predictors are understudied. In this observational, real-life study, work absence of 14,383 asthma and/or COPD patients present in the MAJORICA cohort (Spain) was compared with the general population. Using multivariable regression, we studied the association of work absence with demographic and clinical characteristics. Patients with asthma and/or COPD had more work absence than the general population (15.2% vs 8.9%, p < 0.0001). Patients with asthma had more often periods of work absence compared to patients with COPD (16.0% vs 12.8%, p < 0.0001). The number of days absent were, however, less in asthma than in COPD (median: 15 days [IQR: 5-51] vs 39 days [IQR: 13-134], p < 0.001). Patients with asthma-COPD overlap were in between (14.5% with absence; median: 27 days [IQR: 10-82]). Comorbid anxiety, allergic rhinitis, and sleep apnoea were independently associated with more work absence.

Indexed as

AsthmaPulmonary Disease, Chronic ObstructiveRhinitis, AllergicCohort StudiesEfficiencyHumans

Identifiers

PMID33594082
PMCPMC7887233

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.