Evidence map›Paper›PMID 33594071›Full record

ArticleNature communications2021

A scalable physician-level deep learning algorithm detects universal trauma on pelvic radiographs.

Chi-Tung Cheng, Yirui Wang, Huan-Wu Chen, Po-Meng Hsiao, Chun-Nan Yeh, Chi-Hsun Hsieh, Shun Miao, Jing Xiao, Chien-Hung Liao, Le Lu

Abstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chi-Tung Cheng *Department of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Linkou, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0002-2697-4642
Yirui Wang *PAII Inc, Bethesda, MD, USA.ORCID 0000-0002-9804-8736
Huan-Wu ChenDivision of Emergency and Critical Care Radiology, Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Po-Meng HsiaoNew Taipei Municipal TuCheng Hospital, New Taipei city, Taiwan.
Chun-Nan YehDepartment of Surgery, Chang Gung Memorial Hospital, Linkou, Chang Gung University, Taoyuan, Taiwan.
Chi-Hsun HsiehDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Linkou, Chang Gung University, Taoyuan, Taiwan.
Shun MiaoPAII Inc, Bethesda, MD, USA.
Jing XiaoPAII Inc, Bethesda, MD, USA.
Chien-Hung LiaoDepartment of Trauma and Emergency Surgery, Chang Gung Memorial Hospital, Linkou, Chang Gung University, Taoyuan, Taiwan. surgymet@gmail.com.ORCID 0000-0003-2812-9773
Le LuPAII Inc, Bethesda, MD, USA.ORCID 0000-0002-6799-9416

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pelvic radiograph (PXR) is essential for detecting proximal femur and pelvis injuries in trauma patients, which is also the key component for trauma survey. None of the currently available algorithms can accurately detect all kinds of trauma-related radiographic findings on PXRs. Here, we show a universal algorithm can detect most types of trauma-related radiographic findings on PXRs. We develop a multiscale deep learning algorithm called PelviXNet trained with 5204 PXRs with weakly supervised point annotation. PelviXNet yields an area under the receiver operating characteristic curve (AUROC) of 0.973 (95% CI, 0.960-0.983) and an area under the precision-recall curve (AUPRC) of 0.963 (95% CI, 0.948-0.974) in the clinical population test set of 1888 PXRs. The accuracy, sensitivity, and specificity at the cutoff value are 0.924 (95% CI, 0.912-0.936), 0.908 (95% CI, 0.885-0.908), and 0.932 (95% CI, 0.919-0.946), respectively. PelviXNet demonstrates comparable performance with radiologists and orthopedics in detecting pelvic and hip fractures.

Indexed as

AlgorithmsDeep LearningPhysiciansAdultAgedFemaleHip FracturesHumansMaleMiddle AgedPelvisROC CurveWounds and Injuries

Identifiers

PMID33594071
PMCPMC7887334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.