ArticlemBio2021
High-Resolution Differentiation of Enteric Bacteria in Premature Infant Fecal Microbiomes Using a Novel rRNA Amplicon.
Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 49 citations in OpenAlex.
- Article
- Comparison of a long-read amplicon sequencing approach to short-read amplicons for microbiome analysis.Microbiology spectrum · 2026Article
- Long-Read Sequencing for Species-Level Resolution of the Equine Gut Microbiota Reveals the Need for Improved Databases.Animals : an open access journal from MDPI · 2026Article
- A Systems Approach to Endophyte-Mediated Plant Holobiont and Microbiome Dynamics.Plants (Basel, Switzerland) · 2026Review
- MHASS: Microbiome HiFi Amplicon Sequencing Simulator.Bioinformatics (Oxford, England) · 2026Article
- Correction: Comprehensive analysis of gut microbiota and fecal metabolites in patients with autism spectrum disorder.Frontiers in microbiology · 2026Article
- Refining microbiome resolution: KoSCAPEGut microbes · 2025Article
- Fungus-infected Meiogyne flowers offer a brood site for beetle pollinators in a tripartite nursery pollination system.Annals of botany · 2025Article
- Comparison of a long-read amplicon sequencing approach to short-read amplicons for microbiome analysis.bioRxiv : the preprint server for biology · 2025Article
- Source-tracking Klebsiella outbreaks in premature infants using a novel amplicon fingerprinting method.Antimicrobial resistance and infection control · 2025Article
- Differential susceptibility to colonic ulceration in mice with genetic deletion ofResearch square · 2025Article
- Superior Resolution Profiling of the Coleofasciculus Microbiome by Amplicon Sequencing of the Complete 16S rRNA Gene and ITS Region.Environmental microbiology reports · 2025Article
- Comparison of Lysis and Amplification Methodologies for Optimal 16S rRNA Gene Profiling for Human and Mouse Microbiome Studies.International journal of molecular sciences · 2025Article
- Influence of sewage effluent discharge on putative pathogen community in drinking water sources: insights from full-length 16S rRNA gene amplicon sequencing.Journal of water and health · 2025Article
- Cecal microbiome transplantation without antibiotic preconditioning standardizes murine microbiomes.Frontiers in microbiology · 2025Article
- Mitochondrion-Mediated Metabolism and Microbiome Biodiversity Influence Autism-alike Behaviors.Journal of neurology & translational neuroscience · 2025Article
- Pregnancy during COVID 19 pandemic associated with differential gut microbiome composition as compared to pre-pandemic.Scientific reports · 2024Article
- Temporal Investigation of the Maternal Origins of Fetal Gut Microbiota.Microorganisms · 2024Article
- Updates and Current Challenges in Reproductive Microbiome: A Comparative Analysis between Cows and Women.Animals : an open access journal from MDPI · 2024Review
- GROND: a quality-checked and publicly available database of full-length 16S-ITS-23S rRNA operon sequences.Microbial genomics · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Identifying and tracking microbial strains as microbiomes evolve are major challenges in the field of microbiome research. We utilized a new sequencing kit that combines DNA extraction with PCR amplification of a large region of the rRNA operon and downstream bioinformatic data analysis. Longitudinal microbiome samples of coadmitted twins from two different neonatal intensive care units (NICUs) were analyzed using an ∼2,500-base amplicon that spans the 16S and 23S rRNA genes and mapped to a new, custom 16S-23S rRNA database. Amplicon sequence variants (ASVs) inferred using DADA2 provided sufficient resolution for the differentiation of rRNA variants from closely related but not previously sequenced
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.