Evidence map›Paper›PMID 33593926›Full record

ArticleLearning & memory (Cold Spring Harbor, N.Y.)2021

Retrograde enhancement of episodic learning by a postlearning stimulus.

Julian Quintanilla, Brittney M Cox, Christine M Gall, Stephen V Mahler, Gary Lynch

Abstract read
In one paragraph

Article in Learning & memory (Cold Spring Harbor, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Microglia Support Both the Singular Form of LTP Expressed by the Lateral Perforant Path and Episodic Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Contributions of site- and sex-specific LTPs to everyday memory.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  3. Sex differences in the context dependency of episodic memory.Frontiers in behavioral neuroscience · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Julian QuintanillaDepartment of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697, USA.
Brittney M CoxDepartment of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697, USA.
Christine M GallDepartment of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697, USA.
Stephen V MahlerDepartment of Neurobiology and Behavior, University of California at Irvine, Irvine, California 92697, USA.
Gary LynchDepartment of Anatomy and Neurobiology, University of California at Irvine, Irvine, California 92697, USA.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Impact of Cannabinoid Across the Lifespan (ICAL)P50DA044118 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI Stephen Vincent Mahler · 2018 to 2026
$18.2M
Loss and rescue of endocannabinoid-dependent LTP and memory in Fragile-X model miceR01HD089491 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI GALL, CHRISTINE M, LYNCH, GARY S · 2016 to 2020
$2.2M
NCATS NIH HHS UL1 TR001414NICHD NIH HHS R01 HD089491NIDA NIH HHS P50 DA044118
6 · The paper itself

Abstract

Evidence suggests encoding of recent episodic experiences may be enhanced by a subsequent salient event. We tested this hypothesis by giving rats a 3-min unsupervised experience with four odors and measuring retention after different delays. Animals recognized that a novel element had been introduced to the odor set at 24 but not 48 h. However, when odor sampling was followed within 5 min by salient light flashes or bedding odor, the memory lasted a full 2 d. These results describe a retroactive influence of salience to promote storage of episodic information and introduce a unique model for studying underlying plasticity mechanisms.

Indexed as

Memory, EpisodicAnimalsBehavior, AnimalMaleOlfactory PerceptionRatsRats, Long-EvansRetention, PsychologyTime Factors

Identifiers

PMID33593926
PMCPMC7888236

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.