ArticleProceedings of the National Academy of Sciences of the United States of America2021
Dissipation bounds the amplification of transition rates far from equilibrium.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Interpretable Thermodynamic Score-based Classification of Relaxation Excursions.bioRxiv : the preprint server for biology · 2025Article
- Fluctuation structure predicts genome-wide perturbation outcomes.Research square · 2025Article
- Nonequilibrium design strategies for functional colloidal assemblies.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Inferring equilibrium transition rates from nonequilibrium protocols.Biophysical journal · 2023Article
- Dissipation bounds the amplification of transition rates far from equilibrium.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
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2 authors.
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Abstract
Complex systems can convert energy imparted by nonequilibrium forces to regulate how quickly they transition between long-lived states. While such behavior is ubiquitous in natural and synthetic systems, currently there is no general framework to relate the enhancement of a transition rate to the energy dissipated or to bound the enhancement achievable for a given energy expenditure. We employ recent advances in stochastic thermodynamics to build such a framework, which can be used to gain mechanistic insight into transitions far from equilibrium. We show that under general conditions, there is a basic speed limit relating the typical excess heat dissipated throughout a transition and the rate amplification achievable. We illustrate this tradeoff in canonical examples of diffusive barrier crossings in systems driven with autonomous and deterministic external forcing protocols. In both cases, we find that our speed limit tightly constrains the rate enhancement.
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