ArticleBMC gastroenterology2021
Diagnostic yield of colon capsule endoscopy for Crohn's disease lesions in the whole gastrointestinal tract.
Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- The diagnostic yield of pan-enteric capsule endoscopy in inflammatory bowel disease: A systematic review and meta-analysis.Journal of gastroenterology and hepatology · 2022Pooled it
- Immune-evasive stem cells: engineering tolerance and reprogramming microenvironments for regenerative therapy.Stem cell research & therapy · 2026Review
- The Diagnostic Accuracy of Colon Capsule Endoscopy in Inflammatory Bowel Disease-A Systematic Review and Meta-Analysis.Diagnostics (Basel, Switzerland) · 2024Review
- The Diagnostic Utility of Biochemical Markers and Intestinal Ultrasound Compared with Endoscopy in Patients with Crohn's Disease and Ulcerative Colitis: A Systemic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Pan-Enteric Capsule Endoscopy: Current Applications and Future Perspectives.GE Portuguese journal of gastroenterology · 2024Review
- Capsule endoscopy and panendoscopy: A journey to the future of gastrointestinal endoscopy.World journal of gastroenterology · 2024Article
- Deep learning and minimally invasive inflammatory activity assessment: a proof-of-concept study for development and score correlation of a panendoscopy convolutional network.Therapeutic advances in gastroenterology · 2024Article
- Smart Endoscopy Is Greener Endoscopy: Leveraging Artificial Intelligence and Blockchain Technologies to Drive Sustainability in Digestive Health Care.Diagnostics (Basel, Switzerland) · 2023Review
- Capsule Endoscopy in Inflammatory Bowel Disease: Panenteric Capsule Endoscopy and Application of Artificial Intelligence.Gut and liver · 2023Article
- Middle small-bowel segment Lewis score may predict long-term outcomes among patients with quiescent Crohn's disease.Therapeutic advances in gastroenterology · 2023Article
- Performance of a Deep Learning System for Automatic Diagnosis of Protruding Lesions in Colon Capsule Endoscopy.Diagnostics (Basel, Switzerland) · 2022Article
- Review: Colon Capsule Endoscopy in Inflammatory Bowel Disease.Diagnostics (Basel, Switzerland) · 2022Review
- Colon capsule for panendoscopy: a narrow window of opportunity.Endoscopy international open · 2021Article
- Capsule Endoscopy in Inflammatory Bowel Disease: When? To Whom?Diagnostics (Basel, Switzerland) · 2021Review
- Small Bowel Volvulus as Delayed Presentation of Undiagnosed Crohn's Disease: A Case Report.Clinical practice and cases in emergency medicine · 2021Article
- Capsule Endoscopy in Crohn's Disease-From a Relative Contraindication to Habitual Monitoring Tool.Diagnostics (Basel, Switzerland) · 2021Review
- Examination of Entire Gastrointestinal Tract: A Perspective of Mouth to Anus (M2A) Capsule Endoscopy.Diagnostics (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCrohn's disease (CD) can involve the upper gastrointestinal (GI) tract as well as the small and large bowel. PillCam colon capsule endoscopy (PCCE-2) enables observation of the whole GI tract, but its diagnostic yield for CD lesions in the whole GI tract remains unknown.
aimTo elucidate the diagnostic yield of PCCE-2 in patients with CD.
methodsPatients with CD who underwent PCCE-2 and double-balloon endoscopy (DBE) using oral and anal approaches were evaluated for CD lesions in the whole GI tract. We divided the small bowel into three segments (jejunum, ileum, and terminal ileum), and the large bowel into four segments (right colon, transverse colon, left colon, rectum). Detection of ulcer scars, erosion, ulcers, bamboo joint-like appearance, and notch-like appearance was assessed in each segment. The diagnostic yield of PCCE-2 was analyzed based on the DBE results as the gold standard.
resultsOf the total 124 segments, the sensitivities of PCCE-2 for ulcer scars, erosion, and ulcers were 83.3%, 93.8%, and 88.5%, respectively, and the specificities were 76.0%, 78.3%, and 81.6%, respectively. For the 60 small bowel segments, the sensitivities were 84.2%, 95.5%, and 90.0%, respectively, and the specificities were 63.4%, 86.8%, and 87.5%, respectively. For the 64 large bowel segments, the sensitivities were 80.0%, 90.0%, and 83.3%, respectively, and the specificities were 84.7%, 72.2%, and 77.6%, respectively.
conclusionPCCE-2 provides a high diagnostic yield for lesions in the whole GI tract of patients with CD. Thus, we recommend its use as a pan-enteric tool in clinical settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.