Evidence map›Paper›PMID 33593148›Full record

ArticleInnate immunity2021

Matrix metalloproteinase-9 -1562 C/T polymorphism is associated with the risk of sepsis in a Chinese population: A retrospective study.

Cuijuan Zheng, Jiayu Wang, Shouxiang Xie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. A functionalFrontiers in medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cuijuan ZhengDepartment of Anaesthesiology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, China.
Jiayu WangDepartment of Anaesthesiology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, China.
Shouxiang XieDepartment of Emergency, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, China.ORCID 0000-0002-8275-0707
Huaian First People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matrix metalloproteinase-9 (MMP-9) has been shown to participate in the pathogenesis of sepsis. In this study, we recruited 312 sepsis patients and 413 controls to explore the relationship between sepsis risk and the MMP-9 -1562 C/T polymorphism in Han Chinese. The PCR restriction fragment length polymorphism method was used for genotyping. Our data indicated that the MMP-9 -1562 C/T polymorphism was related with the risk of sepsis (CT vs. CC:

Indexed as

GenotypePopulation GroupsAgedChinaCigarette SmokingFemaleGene FrequencyGenetic Association StudiesGenetic Predisposition to DiseaseHumansMaleMatrix Metalloproteinase 9Middle AgedPolymorphism, GeneticRetrospective StudiesRiskMatrix Metalloproteinase 9-1562 C/T polymorphismMMP-9retrospective studyrisksepsis

Identifiers

PMID33593148
PMCPMC8054153
OpenAlexW3132183138

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.