Evidence map›Paper›PMID 33592783›Full record

ArticleTalanta2021

Synthesis of polystyrene-based fluorescent quantum dots nanolabel and its performance in H5N1 virus and SARS-CoV-2 antibody sensing.

Chengfei Li, Zhong Zou, Huiqin Liu, Yu Jin, Guangqiang Li, Chao Yuan, Zhidong Xiao, Meilin Jin

Open access · greenAbstract read
In one paragraph

Article in Talanta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Quantum dots against SARS-CoV-2: diagnostic and therapeutic potentials.Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986) · 2022
    Review
  9. Article
  10. Article
  11. Point-of-care COVID-19 diagnostics powered by lateral flow assay.Trends in analytical chemistry : TRAC · 2021
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Chengfei LiState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, PR China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, PR China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, 430070, PR China.
Zhong ZouState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, PR China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, PR China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, 430070, PR China.
Huiqin LiuCollege of Science, Huazhong Agricultural University, Wuhan, 430070, China.
Yu JinCollege of Science, Huazhong Agricultural University, Wuhan, 430070, China.
Guangqiang LiCollege of Science, Huazhong Agricultural University, Wuhan, 430070, China.
Chao YuanCollege of Science, Huazhong Agricultural University, Wuhan, 430070, China. Electronic address: yuanchao@mail.hzau.edu.cn.
Zhidong XiaoCollege of Science, Huazhong Agricultural University, Wuhan, 430070, China. Electronic address: zdxiao@mail.hzau.edu.cn.
Meilin JinState Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, 430070, PR China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, PR China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, 430070, PR China. Electronic address: jinmeilin@mail.hzau.edu.cn.
Huazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantum dots (QDs) based fluorescent nanobeads are considered as promising materials for next generation point-of-care diagnosis systems. In this study, we carried out, for the first time, the synthesis of QDs nanobeads using polystyrene (PS) nanobead as the template. QDs loading on PS nanobead surface in this method can be readily achieved by the use of polyelectrolyte, avoiding the time-consuming and uncontrollable silane reagents-involved functionalization procedure that conventional synthesis of silica-based QDs nanobeads often suffer from. Notably, the application of QDs nanobeads in suspension microarray for H5N1 virus detection leads to a sensitivity lower than 25 PFU/mL. In addition, QDs nanobead was also incorporated into lateral flow assay for SARS-CoV-2 antibody detection, leading to more than one order of magnitude detection sensitivity as compared to that of commercial one based on colloid gold.

Indexed as

MicrospheresQuantum DotsAntibodies, ViralBiosensing TechniquesCOVID-19Fluorescent DyesHumansInfluenza A Virus, H5N1 SubtypeInfluenza, HumanMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionNanostructuresPolystyrenesSARS-CoV-2Sensitivity and SpecificitySilicon DioxideAntibodies, ViralFluorescent DyesPolystyrenesSilicon DioxideFluorescent lateral flow assayH5N1QDs nanobeadsSARS-CoV-2Suspension microarray

Identifiers

PMID33592783
PMCPMC7831906
OpenAlexW3118831336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.