Evidence map›Paper›PMID 33592677›Full record

ArticleJournal of evaluation in clinical practice2021

Embracing complexity with systems thinking in general practitioners' clinical reasoning helps handling uncertainty.

Erik Stolper, Paul Van Royen, Edmund Jack, Jeroen Uleman, Marcel Olde Rikkert

Abstract read
In one paragraph

Article in Journal of evaluation in clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Integrating Systems and Critical Thinking, Clinical Reasoning, Decision-Making, and Judgement in Dietetic Education: Development of a Conceptual Pilot Model.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  2. Longitudinal integrated clerkships: a hermeneutic literature review.Advances in health sciences education : theory and practice · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Primary health care strengthening through the lens of healthcare system thinking.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. How patients in general practice voice and value their gut feelings about health: a qualitative interview study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2023
    Article
  16. Article
  17. The Future of Burn Care From a Complexity Science Perspective.Journal of burn care & research : official publication of the American Burn Association · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Erik StolperFaculty of Health, Medicine and Life Sciences, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, Netherlands.ORCID 0000-0001-8854-3269
Paul Van RoyenFaculty of Medicine and Health Sciences, Department of Family Medicine and Population Health, University of Antwerp, Antwerp, Belgium.
Edmund JackSouth West Peninsula National Institute for Health Research Applied Research Collaboration and University of Plymouth, Community and Primary Care Group, University of Plymouth, Plymouth, UK.
Jeroen UlemanDeptartment of Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.
Marcel Olde RikkertDeptartment of Geriatric Medicine, Radboud University Medical Center, Nijmegen, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical reasoning in general practice is increasingly challenging because of the rise in the number of patients with multimorbidity. This creates uncertainty because of unpredictable interactions between the symptoms from multiple medical problems and the patient's personality, psychosocial context and life history. Case analysis may then be more appropriately managed by systems thinking than by hypothetic-deductive reasoning, the predominant paradigm in the current teaching of clinical reasoning. Application of "systems thinking" tools such as causal loop diagrams allows the patient's problems to be viewed holistically and facilitates understanding of the complex interactions. We will show how complexity levels can be graded in clinical reasoning and demonstrate where and how systems thinking can have added value by means of a case history.

Indexed as

General PractitionersClinical ReasoningHumansProblem SolvingSystems AnalysisUncertaintyclinical reasoningcomplexity-informedgeneral practicegut feelingsmultimorbidityuncertainty

Identifiers

PMID33592677
PMCPMC8518614

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.