Evidence map›Paper›PMID 33592138›Full record

ArticleImmunity, inflammation and disease2021

Cathepsin K maintains the compartment of bone marrow T lymphocytes in vivo.

Renate Hausinger, Marianne Hackl, Ana Jardon Alvarez, Miriam Kehr, Sandra Romero Marquez, Franziska Hettler, Christian Kehr, Sandra Grziwok, Christina Schreck, Christian Peschel and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, inflammation and disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Renate HausingerTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Marianne HacklTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Ana Jardon AlvarezTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Miriam KehrTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Sandra Romero MarquezTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Franziska HettlerTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Christian KehrTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Sandra GrziwokTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Christina SchreckTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Christian PeschelTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Rouzanna IstvánffyTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.
Robert A J OostendorpTechnical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Internal Medicine III - Hematology and Oncology, Laboratory of Stem Cell Physiology, Munich, Germany.ORCID 0000-0002-4947-0412
TUM Klinikum · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we investigated the influence of the loss of cathepsin K (Ctsk) gene on the hematopoietic system in vitro and in vivo. We found that cultures with lineage

Indexed as

Bone MarrowT-LymphocytesCathepsin KHematopoietic Stem CellsLymphocyte CountCathepsin Kcathepsincathepsin KCTSKhematopoietic stem cellslymphopoiesismarrowmicroenvironmentnichestem cells

Identifiers

PMID33592138
PMCPMC8127559
OpenAlexW3129408370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.