Evidence map›Paper›PMID 33592130›Full record

ArticleCurrent protocols2021

Testing Graphical Causal Models Using the R Package "dagitty".

Ankur Ankan, Inge M N Wortel, Johannes Textor

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Current protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Trial
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  13. Occurrence of COVID-19 and serumGlobal epidemiology · 2024
    Article
  14. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Ankur AnkanDepartment of Tumour Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands.
Inge M N WortelDepartment of Tumour Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands.
Johannes TextorDepartment of Tumour Immunology, Radboud Institute for Molecular Life Sciences, Radboudumc, Nijmegen, The Netherlands.

Funding

KWFRadboudumc
6 · The paper itself

Abstract

Causal diagrams such as directed acyclic graphs (DAGs) are used in several scientific fields to help design and analyze studies that aim to infer causal effects from observational data; for example, DAGs can help identify suitable strategies to reduce confounding bias. However, DAGs can be difficult to design, and the validity of any DAG-derived strategy hinges on the validity of the postulated DAG itself. Researchers should therefore check whether the assumptions encoded in the DAG are consistent with the data before proceeding with the analysis. Here, we explain how the R package 'dagitty', based on the web tool dagitty.net, can be used to test the statistical implications of the assumptions encoded in a given DAG. We hope that this will help researchers discover model specification errors, avoid erroneous conclusions, and build better models. © 2021 The Authors. Basic Protocol 1: Constructing and importing DAG models from the dagitty web interface Support Protocol 1: Installing R, RStudio, and the dagitty package Basic Protocol 2: Testing DAGs against categorical data Basic Protocol 3: Testing DAGs against continuous data Support Protocol 2: Testing DAGs against continuous data with non-linearities Basic Protocol 4: Testing DAGs against a combination of categorical and continuous data.

Indexed as

Models, TheoreticalBiasCausalityConfounding Factors, EpidemiologicData Interpretation, Statisticaldagittydirected acyclic graphs (DAGs)independence testingmodel testing

Identifiers

PMID33592130

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.