ArticleMolecular biology and evolution2021
Herbicide Selection Promotes Antibiotic Resistance in Soil Microbiomes.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
55 citing papers in PubMed, 164 citations in OpenAlex.
- Characterization of defensome genes and mobile genetic Elements in different types of pasture soil agroecosystems from the Brazilian Amazon.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Agricultural Pesticide Exposure and Antimicrobial Resistance inMicroorganisms · 2026Article
- Farming practices exert selection pressures on the resistome of natural populations of house mice.Nature communications · 2026Article
- Glyphosate Promotes the Spread of Antibiotic Resistance Genes in the Intestine: An Overlooked Environmental Risk.Toxics · 2026Article
- Bacteria in Peanut Nodules Under Herbicide and Non-Herbicide Management: Isolation, Identification, and Screening of Plant Growth-Promoting Traits.Microorganisms · 2026Article
- How Glyphosate and Its Derivatives Influence Antimicrobial Resistance Emergence and Transmission: A One Health Perspective.Antibiotics (Basel, Switzerland) · 2026Review
- Impacts of drought and manure fertilization on soil and radish resistomes.Scientific reports · 2026Article
- The hidden role of rhizospheric viruses in promoting nitrogen fixation in soils.Nature communications · 2026Article
- The Role of the Environmental Microbiome in Modulating the Spread of Antimicrobial Resistance.Current microbiology · 2026Review
- Nonclinical RhizobacteriaJournal of agricultural and food chemistry · 2026Article
- Glyphosate resistance as a potential driver for the dissemination of multidrug-resistant clinical strains.Frontiers in microbiology · 2026Article
- Glyphosate-based herbicide exposure triggers genetic adaptation but not diversity collapse within bacterioplankton species.ISME communications · 2026Article
- Antimicrobial resistance in plant-associated microbial communities: mechanisms, ecology, and one health implications.Frontiers in microbiology · 2026Review
- Fosfomycin Resistance: An Update on the Anthropogenic Impact Through Agriculture.Pathogens (Basel, Switzerland) · 2025Review
- Effects of predatory mite biocontrols on the dispersal of antibiotic resistomes and virulence factors in tea garden soils.Microbiome · 2025Article
- Exploring the Relationship Between Farmland Management and Manure-Derived Antibiotic Resistance Genes and Their Prevention and Control Strategies.Antibiotics (Basel, Switzerland) · 2025Review
- Ecological consequences of antimicrobial residues and bioactive chemicals on antimicrobial resistance in agroecosystems.Journal of advanced research · 2025Review
- Tolerance to Herbicides and Resistance to Antibacterial Drugs of Bacterial Isolates From the Guarani Aquifer System (Brazil).Environmental microbiology · 2025Article
- Exploring the Ecological Impacts of Herbicides on Antibiotic Resistance Genes and Microbial Communities.Life (Basel, Switzerland) · 2025Article
- Plant Diversity Reduces the Risk of Antibiotic Resistance Genes in Agroecosystems.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
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Authors and funding
15 authors at 5 institutions in 3 countries.
Funding
Abstract
Herbicides are one of the most widely used chemicals in agriculture. While they are known to be harmful to nontarget organisms, the effects of herbicides on the composition and functioning of soil microbial communities remain unclear. Here we show that application of three widely used herbicides-glyphosate, glufosinate, and dicamba-increase the prevalence of antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) in soil microbiomes without clear changes in the abundance, diversity and composition of bacterial communities. Mechanistically, these results could be explained by a positive selection for more tolerant genotypes that acquired several mutations in previously well-characterized herbicide and ARGs. Moreover, herbicide exposure increased cell membrane permeability and conjugation frequency of multidrug resistance plasmids, promoting ARG movement between bacteria. A similar pattern was found in agricultural soils across 11 provinces in China, where herbicide application, and the levels of glyphosate residues in soils, were associated with increased ARG and MGE abundances relative to herbicide-free control sites. Together, our results show that herbicide application can enrich ARGs and MGEs by changing the genetic composition of soil microbiomes, potentially contributing to the global antimicrobial resistance problem in agricultural environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.