ArticleMolecular biology and evolution2021
Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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40 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- A macrogenetic analysis of isolation mechanisms shaping genetic divergence in mammals.The Journal of heredity · 2026Pooled it
- From genes to collective modes: biological constraints shape metabolic evolution.bioRxiv : the preprint server for biology · 2026Article
- The Japanese Archipelago sheltered cave lions, not tigers, during the Late Pleistocene.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Assessing Genotype Imputation Methods for Low-Coverage Sequencing Data in Populations With Differing Relatedness and Inbreeding Levels.Molecular ecology resources · 2025Article
- Exceedingly low genetic diversity in snow leopards due to persistently small population size.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Conservation genomics of two endangered buntings reveal genetic diversity before and after severe population declines.BMC biology · 2025Article
- Research on the Historical Dynamics of Baicheng Oil Chicken Populations.Animals : an open access journal from MDPI · 2025Article
- Linking Measures of Inbreeding and Genetic Load to Demographic Histories Across Three Species of Bears.Evolutionary applications · 2025Article
- Natural dispersal is better than translocation for reducing risks of inbreeding depression in eastern black rhinoceros (Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Genomic insights and the conservation potential of captive breeding: The case of Chinese alligator.Science advances · 2025Article
- Parameterizing Pantherinae: De Novo Mutation Rate Estimates from Panthera and Neofelis Pedigrees.Genome biology and evolution · 2025Article
- A Pipeline and Recommendations for Population and Individual Diagnostic SNP Selection in Non-Model Species.Molecular ecology resources · 2025Article
- Unraveling the genomic diversity and admixture history of captive tigers in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Toward telomere-to-telomere cat genomes for precision medicine and conservation biology.Genome research · 2024Review
- Genome sequencing of captive white tigers from Bangladesh.BMC genomic data · 2024Article
- Insights for the Captive Management of South China Tigers Based on a Large-Scale Genetic Survey.Genes · 2024Article
- Ancient DNA reveals genetic admixture in China during tiger evolution.Nature ecology & evolution · 2023Article
- How genomic insights into the evolutionary history of clouded leopards inform their conservation.Science advances · 2023Article
- Can Bengal Tiger (Ecology and evolution · 2023Article
- Population genomic analysis provides evidence of the past success and future potential of South China tiger captive conservation.BMC biology · 2023Article
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Authors and funding
25 authors at 13 institutions in 5 countries.
Funding
Abstract
Species conservation can be improved by knowledge of evolutionary and genetic history. Tigers are among the most charismatic of endangered species and garner significant conservation attention. However, their evolutionary history and genomic variation remain poorly known, especially for Indian tigers. With 70% of the world's wild tigers living in India, such knowledge is critical. We re-sequenced 65 individual tiger genomes representing most extant subspecies with a specific focus on tigers from India. As suggested by earlier studies, we found strong genetic differentiation between the putative tiger subspecies. Despite high total genomic diversity in India, individual tigers host longer runs of homozygosity, potentially suggesting recent inbreeding or founding events, possibly due to small and fragmented protected areas. We suggest the impacts of ongoing connectivity loss on inbreeding and persistence of Indian tigers be closely monitored. Surprisingly, demographic models suggest recent divergence (within the last 20,000 years) between subspecies and strong population bottlenecks. Amur tiger genomes revealed the strongest signals of selection related to metabolic adaptation to cold, whereas Sumatran tigers show evidence of weak selection for genes involved in body size regulation. We recommend detailed investigation of local adaptation in Amur and Sumatran tigers prior to initiating genetic rescue.
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