Evidence map›Paper›PMID 33592005›Full record

SynthesisPloS one2021

Cervical length varies considering different populations and gestational outcomes: Results from a systematic review and meta-analysis.

T G Bortoletto, T V Silva, A Borovac-Pinheiro, C M Pereira, A D Silva, M S França, A R Hatanaka, J P Argenton, R Passini, B W Mol and 2 more

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Sleep and affect: A conceptual review.Sleep medicine reviews · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

T G BortolettoSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
T V SilvaSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
A Borovac-PinheiroSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
C M PereiraSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
A D SilvaSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID 0000-0001-5507-3846
M S FrançaDepartment of Obstetrics and Gynaecology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.ORCID 0000-0001-5145-1061
A R HatanakaDepartment of Obstetrics and Gynaecology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil.
J P ArgentonSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
R PassiniSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
B W MolDepartment of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.ORCID 0000-0001-8337-550X
J G CecattiSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
R C PacagnellaSchool of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.ORCID 0000-0002-5739-0009
Universidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal de São Paulo · BRMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe uterine cervical length is an important risk factor for preterm birth. The aim of this study was to assess cervical length distribution in women with singleton pregnancies, measured by transvaginal ultrasound between 16 and 24 weeks, and its association with population characteristics. MATERIALS AND

methodsWe searched electronic databases and other sources for studies published from April 1, 1990 to July 21, 2020. Of the 2019 retrieved publications, full-text versions of 137 articles were considered. We included 77 original articles that reported cervical length measurements of 363,431 women. The main aim of this study was to identify the pattern of cervical length in different populations. We collected demographic and clinical data concerning the population, in addition to information regarding the ultrasound examination and cervical length measurement. Regarding study bias, 56 were at low risk of bias and 21 were at medium risk of bias.

resultsThe meta-analysis included 57 articles with data from 158,346 women. The mean cervical length was 37.96. mm (95% CI [36.68, 39.24]). Cervical length was shorter in women from Africa and Asia, in those from low-income countries, with a lower body weight, and in those who delivered before 37 gestational weeks. We found that the cervical length from pooled studies is longer than that usually discussed in the literature. Regarding limitations, we had difficulty assessing our main variable because there was no consistent pattern in the way authors reported cervical length measurement. Another limitation was the great heterogeneity between studies.

conclusionsThe use of a single cutoff value to define a short cervix diagnosis, an important risk factor for preterm birth, may not be correct and cervical length must be considered according to maternal population characteristics. Future studies should identify different specific curves and cutoff values for cervical length in different populations. This meta-analysis was registered in the PROSPERO database under CRD42017070246 at https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=70246.

Indexed as

Gestational AgeAfricaAsiaCervical Length MeasurementCervix UteriFemaleHumansInfant, NewbornPregnancyPremature BirthRisk Factors

Identifiers

PMID33592005
PMCPMC7886126
OpenAlexW3130723463

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.