Evidence map›Paper›PMID 33591820›Full record

ArticleJCO global oncology2021

Identifying Priorities for Harmonizing Guidelines for the Long-Term Surveillance of Childhood Cancer Survivors in the Chinese Children Cancer Group (CCCG).

Yin Ting Cheung, Hui Zhang, Jiaoyang Cai, Lung Wai Phillip Au-Doung, Lok Sum Yang, Cuixia Yan, Fen Zhou, Xiaojuan Chen, Xianmin Guan, Ching-Hon Pui and 2 more

Open access · goldAbstract read
In one paragraph

Article in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Article
  6. Review
  7. Supportive care needs of parents caring for children with leukemia: a latent profile analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
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  14. Article
  15. Awareness of diagnosis, treatment and risk of late effects in Chinese survivors of childhood cancer in Hong Kong.Health expectations : an international journal of public participation in health care and health policy · 2021
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Yin Ting CheungSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0001-9874-8938
Hui ZhangDepartment of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, China.ORCID 0000-0001-8791-5753
Jiaoyang CaiKey Laboratory of Pediatric Hematology and Oncology Ministry of Health, Department of Hematology and Oncology, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.ORCID 0000-0003-2051-4044
Lung Wai Phillip Au-DoungSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.
Lok Sum YangSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.
Cuixia YanDepartment of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Fen ZhouPediatric Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiaojuan ChenState Key Laboratory of Experimental Hematology, Department of Paediatrics Haematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xianmin GuanDivision of Hematology, Children's Hospital, Chongqing Medical University, Chongqing, China.
Ching-Hon PuiDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0003-0303-5658
Melissa M HudsonDepartment of Oncology, St Jude Children's Research Hospital, Memphis, TN.ORCID 0000-0001-6984-2407
Chi-Kong LiDepartment of Paediatrics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0002-2810-5758
Chinese University of Hong Kong · HKGuangzhou Women and Children Medical Center · CNSt. Jude Children's Research Hospital · USChildren's Hospital of Chongqing Medical University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNShanghai Jiao Tong University · CNUnion Hospital · CN

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9M
NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

purposeSurvivors of childhood cancer often experience treatment-related chronic health conditions. Given its vast population, China shares a large proportion of the global childhood cancer burden. Yet, screening and treatment of late effects in survivors of childhood cancer remain underaddressed in most regions of China. This study aimed to identify high-priority late effects for harmonizing screening guidelines within the Chinese Children's Cancer Group (CCCG), as well as barriers and enablers of the implementation of surveillance recommendations in local practice.

methodsTo establish clinical consensus, 12 expert panelists who represent major institutions within the CCCG completed a Delphi survey and participated in a focus group discussion. The survey solicited ratings of the prevalence, severity, and priority for screening of 45 late effects. Major themes identified from the focus group were analyzed using thematic analysis.

resultsThe Delphi survey identified eight high-priority late effects for harmonization within CCCG: osteonecrosis, osteoporosis, left ventricular dysfunction, secondary brain tumors, treatment-related myeloid leukemia, gonadal dysfunction, growth hormone deficiency, and neurocognitive deficits. The common barriers to implementing survivorship programs include lack of support and resources for clinicians to provide follow-up care. Patients were also concerned about privacy issues and lacked awareness of late effects. Many institutions also lacked rehabilitation expertise and referral pathways.

conclusionBy identifying obstacles related to the professional setting, patient behavior, and organization of care, our study identified resources and a framework for establishing collaborative strategies to facilitate follow-up care of childhood cancer survivors in China.

Indexed as

Brain NeoplasmsCancer SurvivorsAftercareChildChinaHumansSurvivors

Identifiers

PMID33591820
PMCPMC8081494
OpenAlexW3131437583

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.