Evidence map›Paper›PMID 33591765›Full record

ArticleOrganic letters2021

Expanding Coefficient: A Parameter To Assess the Stability of Induced-Fit Complexes.

Carmen Talotta, Gerardo Concilio, Margherita De Rosa, Annunziata Soriente, Carmine Gaeta, Antonio Rescifina, Pablo Ballester, Placido Neri

Abstract read
In one paragraph

Article in Organic letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carmen TalottaDipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, via Giovanni Paolo II, 132, I-84084, Fisciano (Salerno), Italy.ORCID http://orcid.org/0000-0002-2142-6305
Gerardo ConcilioDipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, via Giovanni Paolo II, 132, I-84084, Fisciano (Salerno), Italy.
Margherita De RosaDipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, via Giovanni Paolo II, 132, I-84084, Fisciano (Salerno), Italy.ORCID http://orcid.org/0000-0001-7451-5523
Annunziata SorienteDipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, via Giovanni Paolo II, 132, I-84084, Fisciano (Salerno), Italy.ORCID http://orcid.org/0000-0001-6937-8405
Carmine GaetaDipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, via Giovanni Paolo II, 132, I-84084, Fisciano (Salerno), Italy.ORCID http://orcid.org/0000-0002-2160-8977
Antonio RescifinaDipartimento di Scienze del Farmaco e della Salute, Università di Catania, viale Andrea Doria, 6, I-95125 Catania, Italy.ORCID http://orcid.org/0000-0001-5039-2151
Pablo BallesterInstitute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology (BIST), Av. Països Catalans, 16, 43007 Tarragona, Spain.ORCID http://orcid.org/0000-0001-8377-6610
Placido NeriDipartimento di Chimica e Biologia "A. Zambelli", Università di Salerno, via Giovanni Paolo II, 132, I-84084, Fisciano (Salerno), Italy.ORCID http://orcid.org/0000-0003-4319-1727

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we propose a new parameter, the Expanding Coefficient (EC), that can be correlated with the thermodynamic stability of supramolecular complexes governed by weak secondary interactions and obeying the induced-fit model. The EC values show a good linear relationship with the log

Identifiers

PMID33591765
PMCPMC8028309

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.