ArticleJournal of cellular and molecular medicine2021
Red cell distribution width and erythrocyte osmotic stability in type 2 diabetes mellitus.
Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 27 citations in OpenAlex.
- Prevalence and Determinants of Anemia and Iron Deficiency Anemia Among Patients With Diabetes Mellitus in Cameroon: An Analytical Cross-Sectional Study.Health science reports · 2026Article
- A novel AI-coupled flow chamber method quantifying erythrocyte osmotic fragility.Scientific reports · 2026Article
- RAR and infant mortality: a crucial link in cardiac surgery outcomes.Frontiers in immunology · 2026Observational
- Red blood cell distribution width is associated with renal tubular injury in individuals with type 2 diabetes.Journal of diabetes investigation · 2025Article
- Correlation analysis between hemoglobin and type 2 diabetic nephropathy: a two-center retrospective study.Acta diabetologica · 2025Article
- Nonlinear association between red cell distribution width/albumin ratio and peripheral arterial disease in the NHANES: a cross-section study with propensity score matching analysis.Frontiers in cardiovascular medicine · 2025Article
- High hemoglobin-to-red cell distribution width ratio reduces adverse events in patients with pacemaker implantation.BMC cardiovascular disorders · 2024Observational
- The elevation of red blood cell distribution width is an independent prognostic factor for juvenile myelomonocytic leukemia.Blood science (Baltimore, Md.) · 2024Article
- Red blood cell distribution width to albumin ratio associates with prevalence and long-term diabetes mellitus prognosis: an overview of NHANES 1999-2020 data.Frontiers in endocrinology · 2024Article
- A Novel Inflammatory Marker: Relationship Between Red Cell Distribution Width/Albumin Ratio and Vascular Complications in Patients with Type 2 Diabetes Mellitus.Journal of inflammation research · 2024Article
- A case-control study to evaluate hematological indices in blood of diabetic and non-diabetic individuals in Ibb City, Yemen.Scientific reports · 2023Article
- The relationship between red blood cell distribution width and islet β-cell function indexes in patients with latent autoimmune diabetes in adults.BMC endocrine disorders · 2023Article
- Red cell distribution width and its polygenic score in relation to mortality and cardiometabolic outcomes.Frontiers in cardiovascular medicine · 2023Article
- Article
- Erythrocyte osmotic fragility is not linked to vitamin C nutriture in adults with well-controlled type 2 diabetes.Frontiers in nutrition · 2022Article
- Article
- Red cell distribution width and erythrocyte osmotic stability in type 2 diabetes mellitus.Journal of cellular and molecular medicine · 2021Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
This study aimed to investigate the relationship between red cell distribution width (RDW) and erythrocyte osmotic stability in non-diabetic and diabetic individuals in both sexes. The study sample (N = 122) was constituted by 53 type 2 diabetics (DM) and 69 non-diabetics (ND), being 21 and 22 men in each group, respectively. The osmotic stability of erythrocytes was obtained by the variation in saline concentration (dX) capable of determining hypoosmotic lysis. Higher RDW values and lower serum iron concentrations were found in the diabetic group when compared to the non-diabetic volunteers. In the group of diabetic women, RDW was positively correlated with the reticulocyte index, and both RDW and dX were negatively correlated with iron, haemoglobin, transferrin saturation index, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration. In all the groups studied, RDW was positively correlated with dX, especially in the diabetic group, where the correlation was the strongest. RDW elevation in both women and men with type 2 diabetes mellitus was associated with decreased serum iron indicators. Furthermore, RDW has a similar meaning to dX, as small erythrocytes have less haemoglobin, resulting in both an increase of RDW and dX.
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