Evidence map›Paper›PMID 33591600›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2021

Reproducibility study of nocturnal blood pressure dipping in patients with high cardiovascular risk.

Natalia Burgos-Alonso, Maria Victoria Ruiz Arzalluz, Arturo Garcia-Alvarez, Daniel Fernandez-Fernandez de Quincoces, Gonzalo Grandes

Open access · diamondAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Natalia Burgos-AlonsoPrimary Care Research Unit of Bizkaia, BioCruces Bizkaia Health Research Institute, Bilbao, Spain.ORCID 0000-0001-7230-3340
Maria Victoria Ruiz ArzalluzPrimary Care Research Unit of Bizkaia, BioCruces Bizkaia Health Research Institute, Bilbao, Spain.
Arturo Garcia-AlvarezPrimary Care Research Unit of Bizkaia, BioCruces Bizkaia Health Research Institute, Bilbao, Spain.
Daniel Fernandez-Fernandez de QuincocesPrimary Care Research Unit of Bizkaia, BioCruces Bizkaia Health Research Institute, Bilbao, Spain.
Gonzalo GrandesPrimary Care Research Unit of Bizkaia, BioCruces Bizkaia Health Research Institute, Bilbao, Spain.
BioCruces Health research Institute · ESUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been shown that in most people there is a physiological reduction in blood pressure during nighttime sleep, it falling by approximately 10% compared to daytime values (dippers). On the other hand, in some people, there is no nighttime reduction (non-dippers). Various studies have found an association between being a non-dipper and a higher risk of cardiovascular disease, but few have assessed whether the nocturnal pattern is maintained over time. From the database of the TAHPS study, data were available on 225 patients, each of whom underwent 24-hour ambulatory blood pressure monitoring (ABPM) on four occasions over a period of 5 months. We studied the reproducibility of the nocturnal BP dipping pattern with mixed linear analysis and also calculated the concordance in the classification of patients as dippers or non-dippers. The intraclass correlation coefficients between the different ABPM recordings were 0.482 and 0.467 for systolic and diastolic blood pressure, respectively. Two-thirds (67%) and 70% of the patients classified, respectively, as dippers or non-dippers based on systolic and diastolic blood pressure readings in the first ABPM recording were found to have the same classification based on the subsequent recordings. We conclude that the reproducibility of nocturnal dipping patterns and concordance of dipper vs non-dipper status in individual patients is modest and therefore that we should be cautious about recommending treatments or interventions based on these patterns.

Indexed as

Cardiovascular DiseasesHypertensionBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmHeart Disease Risk FactorsHumansReproducibility of ResultsRisk FactorsABPMblood pressuredippernocturnal dippingprospective study

Identifiers

PMID33591600
PMCPMC8678773
OpenAlexW3130751592

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.