Evidence map›Paper›PMID 33591416›Full record

ReviewDer Nervenarzt2022

[ICD-11: changes in the diagnostic criteria of substance dependence].

Andreas Heinz, Melissa Gül Halil, Stefan Gutwinski, Anne Beck, Shuyan Liu

Abstract readReview
In one paragraph

Review in Der Nervenarzt, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The Diagnosis and Treatment of Stimulant-Related Emergencies.Deutsches Arzteblatt international · 2025
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Does compulsion explain addiction?Addiction biology · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andreas HeinzKlinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin, Campus Bonhoefferweg 3, Charitéplatz 1, 10117, Berlin, Deutschland. andreas.heinz@charite.de.
Melissa Gül HalilKlinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin, Campus Bonhoefferweg 3, Charitéplatz 1, 10117, Berlin, Deutschland.
Stefan GutwinskiKlinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin, Campus Bonhoefferweg 3, Charitéplatz 1, 10117, Berlin, Deutschland.
Anne BeckKlinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin, Campus Bonhoefferweg 3, Charitéplatz 1, 10117, Berlin, Deutschland.
Shuyan LiuKlinik für Psychiatrie und Psychotherapie, Charité Universitätsmedizin Berlin, Campus Bonhoefferweg 3, Charitéplatz 1, 10117, Berlin, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn ICD(International Classification of Diseases)-11 the criteria for the diagnosis of substance dependence have been revised.

objectiveDiscussion of the advantages and disadvantages of the revised diagnostic criteria. MATERIAL AND

methodsDiscussion of criteria with respect to neurobiological, social and clinical research.

resultsIn the new ICD-11, harmful drug use and substance dependence remain separate diagnostic categories. Regarding substance dependence, the former six diagnostic criteria are condensed into three pairs, two of which must be fulfilled to diagnose this disorder. Within the pairs, one affirmed symptom or aspect is sufficient for the new criterion to be fulfilled. With reference to scientific findings in the field of addiction, this appears to provide advantages as well as disadvantages. The specificity of the diagnosis of substance dependence might get worse compared to ICD-10, because only one symptom of the syndrome pairs has to be fulfilled in each newly constructed pair in order to fulfill the criterion. Therefore, the risk of false positive diagnosis of substance dependence could increase. This is a potential reason for concern because the definition of ICD-10 "persisting substance use despite clear evidence of overtly harmful consequences", is more broadly reworded in ICD-11 as "substance use often continues despite the occurrence of problems". This criterion may hence simply be fulfilled because a substance is illegal in a certain country. In the largest multinational study in 10 countries concerning concordance of diagnostic systems, alcohol dependence was diagnosed approximately 10% more often using ICD-11 compared to ICD-10.

conclusionIn ICD-11 the well-established distinction between substance dependence and harmful drug use is preserved. Systematic studies are required to assess whether the new diagnostic criteria are clinically helpful or increase social problems by increasing false positive diagnoses of addiction.

Indexed as

AlcoholismBehavior, AddictiveSubstance-Related DisordersDiagnostic and Statistical Manual of Mental DisordersHumansInternational Classification of DiseasesAlcohol use disorderClassificationDiagnosisICD-10ICD-11

Identifiers

PMID33591416
PMCPMC8763741

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.