Evidence map›Paper›PMID 33591402›Full record

ReviewCurrent oncology reports2021

Progress Update in Pediatric Renal Tumors.

Juhi Jain, Kathryn S Sutton, Andrew L Hong

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  7. Review
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  15. Article
  16. Article
  17. Review
  18. Recent Advances in Renal Medullary Carcinoma.International journal of molecular sciences · 2022
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Juhi JainAflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.
Kathryn S SuttonAflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA.
Andrew L HongAflac Cancer and Blood Disorders Center, Children Healthcare of Atlanta, Atlanta, GA, USA. andrew.hong2@emory.edu.ORCID 0000-0003-0374-1667
Emory University · USEmory Healthcare · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPediatric renal tumors account for 7% of new cancer diagnoses in children. Here, we will review results from recently completed clinical trials informing the current standard of care and discuss targeted and immune therapies being explored for the treatment of high risk or relapsed/refractory pediatric renal malignancies. RECENT

findingsCooperative group trials have continued to make improvements in the care of children with pediatric tumors. In particular, trials that standardize treatment of rare cancers (e.g., bilateral Wilms tumor) have improved outcomes significantly. We have seen improvements in event free and overall survival in recently completed clinical trials for many pediatric renal tumors. Still, there are subsets of rarer cancers where outcomes remain poor and new therapeutic strategies are needed. Future trials aim to balance treatment toxicity with treatment efficacy for those with excellent outcomes while identifying novel therapeutics for those with poor outcomes.

Indexed as

ChildChild WelfareHumansKidney NeoplasmsPrognosisWilms Tumor1q GainAREN0321AREN0532AREN0533AREN0534Clear-cell sarcoma of the kidneyLOH 1p/16qMalignant rhabdoid tumorMesoblastic nephromasPediatric renal tumorsWilms tumor

Identifiers

PMID33591402
OpenAlexW3131841695

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.