Evidence map›Paper›PMID 33591386›Full record

ReviewApplied microbiology and biotechnology2021

Biogenesis of silver nanoparticles to treat cancer, diabetes, and microbial infections: a mechanistic overview.

Bilal Javed, Muhammad Ikram, Fatima Farooq, Tahira Sultana, Zia-Ur-Rehman Mashwani, Naveed Iqbal Raja

Abstract readReview
PubMed Publisher
In one paragraph

Review in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 106 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Multifactorial Role of Phytogenic CeOPlant-environment interactions (Hoboken, N.J.) · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Mitigation of salinity stress in sunflower plants (Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Aflatoxins in Peanut (ACS omega · 2024
    Review
  16. Review
  17. Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Bilal Javed *Department of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab, 46300, Pakistan. javedbilal87@gmail.com.ORCID http://orcid.org/0000-0002-9566-1498
Muhammad Ikram *Department of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab, 46300, Pakistan.
Fatima FarooqInstitute of Industrial Biotechnology, Government College University, Lahore, Punjab, 54000, Pakistan.
Tahira SultanaDepartment of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab, 46300, Pakistan.
Zia-Ur-Rehman MashwaniDepartment of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab, 46300, Pakistan.
Naveed Iqbal RajaDepartment of Botany, PMAS Arid Agriculture University, Rawalpindi, Punjab, 46300, Pakistan.
Pir Mehr Ali Shah Arid Agriculture University · PKGovernment College University, Lahore · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Green synthesis of silver nanoparticles (SNPs) by harnessing the natural abilities of plant secondary metabolites has advantages over routine physical and chemical synthetic approaches due to their one-step experimental setup to reduce and stabilize the bulk silver into SNPs, biocompatible nature, and therapeutic significance. The unique size, shape, and biochemical functional corona of SNPs embellish them with the potential to perform therapeutic actions by adopting various mechanistic approaches including but not limited to the disruption of the electron transport chain, mitochondrial damage, DNA fragmentation, inhibition of ATP synthase activity, disorganization of the cell membrane, suspension of cellular signaling pathways, induction of apoptosis, and inhibition of enzymes activity. This review elaborates the biogenic synthesis of SNPs in redox chemical reactions by using plant secondary metabolites found in plant extracts. In addition, it explains the synergistic influence of physicochemical reaction parameters such as the temperature, pH, the concentration of the AgNO

Indexed as

Diabetes MellitusMetal NanoparticlesNeoplasmsAnti-Bacterial AgentsGreen Chemistry TechnologyHumansInfectionsPlant ExtractsSilverAnti-Bacterial AgentsPlant ExtractsSilverAntidiabeticBacterial resistanceCancerDiabetic footDrugsMultiple drug resistancePathogens

Identifiers

PMID33591386
OpenAlexW3130839985

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.