Evidence map›Paper›PMID 33591365›Full record

ArticleJAMA network open2021

Trends in Low-Value Health Service Use and Spending in the US Medicare Fee-for-Service Program, 2014-2018.

John N Mafi, Rachel O Reid, Lesley H Baseman, Scot Hickey, Mark Totten, Denis Agniel, A Mark Fendrick, Catherine Sarkisian, Cheryl L Damberg

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JAMA network open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07013175 (WIse CHoices in the Intensive Care Unit, a Cluster Randomized Registry Based Clinical Trial), which is not on this map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
24.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07013175 narecruitingnot on this mapstarted 2025, after this paper: background citation

WIse CHoices in the Intensive Care Unit, a Cluster Randomized Registry Based Clinical Trial

TypeinterventionalSponsorKarolinska InstitutetRan2025 to 2027Enrolled10,000ConditionsCritical Illness, Ventilation, Outcome, DialysisArmsChoosing wisely protocol
3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

  1. Cost of Low-Value Imaging Worldwide: A Systematic Review.Applied health economics and health policy · 2024
    Pooled it
  2. Trial
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  14. Transfiguration of Academic Departments of Medicine.The American journal of medicine · 2025
    Article
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  16. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

John N MafiDivision of General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles.
Rachel O ReidRAND Health Care, RAND Corporation, Boston, Massachusetts.
Lesley H BasemanRAND Health Care, RAND Corporation, Boston, Massachusetts.
Scot HickeyRAND Health Care, RAND Corporation, Santa Monica, California.
Mark TottenRAND Health Care, RAND Corporation, Santa Monica, California.
Denis AgnielRAND Health Care, RAND Corporation, Santa Monica, California.
A Mark FendrickDepartment of Internal Medicine, University of Michigan, Ann Arbor.
Catherine SarkisianDivision of Geriatrics, David Geffen School of Medicine at the University of California, Los Angeles.
Cheryl L DambergRAND Health Care, RAND Corporation, Santa Monica, California.
RAND Corporation · USGeriatric Research Education and Clinical Center · USUniversity of California, Los Angeles · USUniversity of Michigan–Ann Arbor · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
The Effect of Nanoparticle Encapsulated Resveratrol on Treatment of PeriodontitisKL2TR001882 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Elizabeta Nemeth · 2016 to 2026
$13.1M
Midcareer Award in Patient-Oriented Community-Academic Partnered Aging ResearchK24AG047899 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SARKISIAN, CATHERINE A · 2014 to 2025
$2.0M
Leveraging Electronic Health Records to Measure and Reduce Harmful, Low-Value Care Among Older AdultsK76AG064392 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAFI, JOHN · 2020 to 2024
$1.2M
NCATS NIH HHS KL2 TR001882NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR001881NIA NIH HHS K24 AG047899NIA NIH HHS K76 AG064392
6 · The paper itself

Abstract

Importance: Low-value care, defined as care offering no net benefit in specific clinical scenarios, is associated with harmful outcomes in patients and wasteful spending. Despite a national education campaign and increasing attention on reducing health care waste, recent trends in low-value care delivery remain unknown. Objective: To assess national trends in low-value care use and spending. Design, Setting, and Participants: In this cross-sectional study, analyses of low-value care use and spending from 2014 to 2018 were conducted using 100% Medicare fee-for-service enrollment and claims data. Included individuals were aged 65 years or older and continuously enrolled in Medicare parts A, B, and D during each measurement year and the previous year. Data were analyzed from September 2019 through December 2020. Exposure: Being enrolled in fee-for-service Medicare for a period of time, in years. Main Outcomes and Measures: The Milliman MedInsight Health Waste Calculator was used to assess 32 claims-based measures of low-value care associated with Choosing Wisely recommendations and other professional guidelines. The calculator designates services as wasteful, likely wasteful, or not wasteful based on an absence of indication of appropriate use in the claims history; calculator-designated wasteful services were defined as low-value care. Spending was calculated as claim-line level (ie, spending on the low-value service) and claim level (ie, spending on the low-value service plus associated services), adjusting for inflation. Results: Among 21 045 759 individuals with fee-for-service Medicare (mean [SD] age, 77.4 [7.9] years; 12 515 915 [59.5%] women), the percentage receiving any of 32 low-value services decreased from 36.3% (95% CI, 36.3%-36.4%) to 33.6% (95% CI, 33.6%-33.6%) from 2014 to 2018. Uses of low-value services per 1000 individuals decreased from 677.8 (95% CI, 676.2-679.5) to 632.7 (95% CI, 632.6-632.8) from 2014 to 2018. Three services comprised approximately two-thirds of uses among 32 low-value services per 1000 individuals: preoperative laboratory testing decreased from 213.8 (95% CI, 213.4-214.2) to 166.2 (95% CI, 166.2-166.2), while opioids for back pain increased from 154.4 (95% CI, 153.6-155.2) to 182.1 (95% CI, 182.1-182.1) and antibiotics for upper respiratory infections increased from 75.0 (95% CI, 75.0-75.1) to 82 (95% CI, 82.0-82.0). Spending per 1000 individuals on low-value care also decreased, from $52 765.5 (95% CI, $51 952.3-$53 578.6) to $46 921.7 (95% CI, $46 593.7-$47 249.7) at the claim-line level and from $160 070.4 (95% CI, $158 999.8-$161 141.0) to $144 741.1 (95% CI, $144 287.5-$145 194.7) at the claim level. Conclusions and Relevance: This cross-sectional study found that among individuals with fee-for-service Medicare receiving any of 32 measured services, low-value care use and spending decreased marginally from 2014 to 2018, despite a national education campaign in collaboration with clinician specialty societies and increased attention on low-value care. While most use of low-value care came from 3 services, 1 of these was opioid prescriptions, which increased over time despite the harms associated with their use. These findings may represent several opportunities to prevent patient harm and lower spending.

Indexed as

Fee-for-Service PlansMedicareAgedAged, 80 and overAnalgesics, OpioidAnti-Bacterial AgentsBack PainDiagnostic Tests, RoutineFemaleHealth ExpendituresHealth ServicesHumansMalePreoperative CareRespiratory Tract InfectionsUnited StatesAnalgesics, OpioidAnti-Bacterial Agents

Identifiers

PMID33591365
PMCPMC7887655
OpenAlexW3131061841

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.