Evidence map›Paper›PMID 33590900›Full record

ArticleJournal of medical virology2021

Anti-spike S1 receptor-binding domain antibodies against SARS-CoV-2 persist several months after infection regardless of disease severity.

Davide F Bavaro, Paola Laghetti, Eugenio Milano, Gaetano Brindicci, Anna Volpe, Antonella Lagioia, Annalisa Saracino, Laura Monno

Abstract read
In one paragraph

Article in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Davide F BavaroClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.ORCID https://orcid.org/0000-0002-4833-7118
Paola LaghettiClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.
Eugenio MilanoClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.
Gaetano BrindicciClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.
Anna VolpeClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.
Antonella LagioiaClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.
Annalisa SaracinoClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.
Laura MonnoClinic of Infectious Diseases, University Hospital Policlinico, University of Bari, Bari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data regarding the immunological memory and long-time kinetics of immunoglobulin (IgG) against viral nucleoprotein (NP) and spike protein S1 receptor-binding domain (S1RBD) of Severe Acute Respiratory Syndrome-associated Coronavirus 2 (SARS-CoV-2) are lacking. All consecutive COVID-19 patients admitted to our Clinic between March 1, 2020, and May 1, 2020, who were tested at hospital admission for anti-S1RBD and anti-NP IgG were enrolled. Serum samples were tested for anti-SARS-CoV-2 antibodies with the use of two commercially available enzyme-linked immunosorbent assays. Results are expressed as optical density measurements at 450 nm (OD

Indexed as

AgedAntibodies, ViralCOVID-19FemaleHumansMaleMiddle AgedProtein BindingProtein DomainsSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, ViralSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2anti-S1RBDCOVID-19SARS-CoV-2serology

Identifiers

PMID33590900
PMCPMC8014088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.