Evidence map›Paper›PMID 33590604›Full record

ArticleAngewandte Chemie (International ed. in English)2021

Iodide-Mediated Rapid and Sensitive Surface Etching of Gold Nanostars for Biosensing.

Yunlei Xianyu, Yiyang Lin, Qu Chen, Alexis Belessiotis-Richards, Molly M Stevens, Michael R Thomas

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yunlei XianyuCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, Zhejiang, 310058, China.ORCID 0000-0003-1299-3460
Yiyang LinState Key Laboratory of Chemical Resource Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.ORCID 0000-0001-8572-649X
Qu ChenDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Alexis Belessiotis-RichardsDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.
Molly M StevensDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.ORCID 0000-0002-7335-266X
Michael R ThomasDepartment of Materials, Department of Bioengineering and Institute of Biomedical Engineering, Imperial College London, London, SW7 2AZ, UK.ORCID 0000-0001-7795-9648

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iodide-mediated surface etching can tailor the surface plasmon resonance of gold nanostars through etching of the high-energy facets of the nanoparticle protrusions in a rapid and sensitive way. By exploring the underlying mechanisms of this etching and the key parameters influencing it (such as iodide, oxygen, pH, and temperature), we show its potential in a sensitive biosensing system. Horseradish peroxidase-catalyzed oxidation of iodide enables control of the etching of gold nanostars to spherical gold nanoparticles, where the resulting spectral shift in the surface plasmon resonance yields a distinct color change of the solution. We further develop this enzyme-modulated surface etching of gold nanostars into a versatile platform for plasmonic immunoassays, where a high sensitivity is possible by signal amplification via magnetic beads and click chemistry.

Indexed as

Biosensing TechniquesBiocatalysisGoldHorseradish PeroxidaseIodidesMetal NanoparticlesOxidation-ReductionSurface PropertiesGoldHorseradish PeroxidaseIodidesgold nanostarshorseradish peroxidaseiodideplasmonic immunoassaysurface etching

Identifiers

PMID33590604
PMCPMC8251757

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.