Evidence map›Paper›PMID 33590580›Full record

ArticleJournal of applied microbiology2021

Peracetic acid-based disinfectant is the most appropriate solution for a biological decontamination procedure of responders and healthcare workers in the field environment.

A Rybka, A Gavel, T Kroupa, J Meloun, P Prazak, J Draessler, O Pavlis, P Kubickova, L Kratzerova, J Pejchal

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Quantification of peracetic acid (PAA) in the HAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2024
    Article
  4. Article
  5. Article
  6. Direct Inhibition of SARS-CoV-2 Spike Protein by Peracetic Acid.International journal of molecular sciences · 2022
    Article
  7. Article
  8. Is Peracetic Acid Fumigation Effective in Public Transportation?International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

A RybkaDepartment of Biological Defense, Military Health Institute, Armed Forces, Techonin, Czech Republic.
A GavelPopulation Protection Institute of Fire and Rescue Services, Lazne Bohdanec, Czech Republic.
T KroupaPopulation Protection Institute of Fire and Rescue Services, Lazne Bohdanec, Czech Republic.
J MelounHealth Institute, Ústí nad Labem, Czech Republic.
P PrazakDepartment of Informatics and Quantitative Methods, Faculty of Informatics and Management, University of Hradec Kralove, Hradec Kralove, Czech Republic.
J DraesslerDepartment of Informatics and Quantitative Methods, Faculty of Informatics and Management, University of Hradec Kralove, Hradec Kralove, Czech Republic.
O PavlisDepartment of Biological Defense, Military Health Institute, Armed Forces, Techonin, Czech Republic.
P KubickovaDepartment of Biological Defense, Military Health Institute, Armed Forces, Techonin, Czech Republic.
L KratzerovaDepartment of Biological Defense, Military Health Institute, Armed Forces, Techonin, Czech Republic.
J PejchalDepartment of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czech Republic.ORCID https://orcid.org/0000-0003-2228-7922
University of Hradec Králové · CZUniversity of Defence · CZ

Funding

Ministerstvo Obrany České Republiky Long-term development plan Medical Aspects of Weapons of Mass Destruction of the Faculty of Military Health SciencesMinisterstvo Vnitra České Republiky VI20172020095
6 · The paper itself

Abstract

aimsAn effective decontamination procedure of personnel wearing personal protective equipment is required by CBRN responders and healthcare workers when dealing with biological warfare agents or natural outbreaks caused by highly contagious pathogens. This study aimed to identify critical factors affecting the efficacy of peracetic acid (PAA)-based disinfectants and products containing either hydrogen peroxide or sodium hypochlorite under the same conditions. METHODS AND

resultsThe influence of concentration, application (contact) time, erroneous human behaviour, interfering substance, technical assets and weather conditions on disinfection efficacy against Bacillus subtilis spores were assessed in 14 experimental groups. Residual contamination of protective suits was measured to provide responders with readily understandable information (up to 100 colony forming units classified a suit as disinfected). Weather conditions, short application time and erroneous human behaviour substantially affected the effectiveness of PAAs (P < 0·05). Non-PAA-based disinfectants (either liquid or foam) did not reach comparable efficacy (P < 0·001).

conclusionsPeracetic acid was effective at a concentration of 6400-8200 ppm and an application time of 4 min. SIGNIFICANCE AND IMPACT OF THE STUDY: The study provides operationally relevant data for the use of PAA-based disinfectants in preparedness planning and management of biological incidents and natural outbreaks.

Indexed as

DecontaminationDisinfectantsPeracetic AcidPersonal Protective EquipmentDisinfectionHealth PersonnelHumansHydrogen PeroxideSpores, BacterialDisinfectantsHydrogen PeroxidePeracetic Acidantimicrobialsbacillusbacterial sporesbiocontrolCBRN respondersdecontaminationdisinfectionerroneous behaviourperacetic acidpersonal protective equipment

Identifiers

PMID33590580
PMCPMC8451822
OpenAlexW3129289534

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.