Evidence map›Paper›PMID 33590562›Full record

ArticleMovement disorders : official journal of the Movement Disorder Society2021

Is Pre-Symptomatic Immunosuppression Protective in CSF1R-Related Leukoencephalopathy?

Philip W Tipton, E Richard Stanley, Violeta Chitu, Zbigniew K Wszolek

Open access · greenAbstract read
In one paragraph

Article in Movement disorders : official journal of the Movement Disorder Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. The Primary Microglial Leukodystrophies: A Review.International journal of molecular sciences · 2022
    Review
  11. Prophylactic Allogeneic Hematopoietic Stem Cell Therapy for CSF1R-Related Leukoencephalopathy.Movement disorders : official journal of the Movement Disorder Society · 2022
    Article
  12. Observational
  13. Review
  14. Review
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Philip W TiptonDepartment of Neurology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-4084-2248
E Richard StanleyDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
Violeta ChituDepartment of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, USA.
Zbigniew K WszolekDepartment of Neurology, Mayo Clinic, Jacksonville, Florida, USA.
Albert Einstein College of Medicine · USJacksonville College · USMayo Clinic · US

Funding

SUPPORT FOR THE ROSE F KENNEDY IDDRC P50P50HD105352 · NICHD · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Julie Secombe · 2021 to 2026
$7.0M
Analysis of a mouse model of adult-onset leukoencephalopathy with axonal spheroids and pigmented glia.R01NS091519 · NINDS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STANLEY, E. RICHARD · 2015 to 2019
$2.5M
NICHD NIH HHS P50 HD105352NINDS NIH HHS R01 NS091519
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeukoencephalopathiesHumansImmunosuppression TherapyMicrogliacorticosteroid; microglia; CSF1R related leukoencephalopathy

Identifiers

PMID33590562
PMCPMC8547119
OpenAlexW3129912935

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.