Evidence map›Paper›PMID 33590519›Full record

ArticleRisk analysis : an official publication of the Society for Risk Analysis2021

Health and Economic Outcomes Associated with Polio Vaccine Policy Options: 2019-2029.

Dominika A Kalkowska, Kimberly M Thompson

Open access · greenAbstract read
In one paragraph

Article in Risk analysis : an official publication of the Society for Risk Analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Coordinated global cessation of oral poliovirus vaccine use: Options and potential consequences.Risk analysis : an official publication of the Society for Risk Analysis · 2024
    Review
  5. Article
  6. Article
  7. Article
  8. Modeling and Managing Poliovirus Risks: We are Where we are….Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  9. An Updated Economic Analysis of the Global Polio Eradication Initiative.Risk analysis : an official publication of the Society for Risk Analysis · 2021
    Article
  10. Health Economic Analysis of Antiviral Drugs in the Global Polio Eradication Endgame.Medical decision making : an international journal of the Society for Medical Decision Making
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Dominika A KalkowskaKid Risk, Inc., Orlando, FL, USA.
Kimberly M ThompsonKid Risk, Inc., Orlando, FL, USA.
Orlando Health · US

Funding

CGH CDC HHS U2R GH001913
6 · The paper itself

Abstract

The polio endgame remains complicated, with many questions about future polio vaccines and national immunization policies. We simulated possible future poliovirus vaccine routine immunization policies for countries stratified by World Bank Income Levels and estimated the expected costs and cases using an updated integrated dynamic poliovirus transmission, stochastic risk, and economic model. We consider two reference cases scenarios: one that achieves the eradication of all wild polioviruses (WPVs) by 2023 and one in which serotype 1 WPV (WPV1) transmission continues. The results show that the addition of inactivated poliovirus vaccine (IPV) to routine immunization in all countries substantially increased the expected costs of the polio endgame, without substantially increasing its expected health or economic benefits. Adding a second dose of IPV to the routine immunization schedules of countries that currently include a single IPV dose further increases costs and does not appear economically justified in the reference case that does not stop WPV transmission. For the reference case that includes all WPV eradication, adding a second IPV dose at the time of successful oral poliovirus vaccine (OPV) cessation represents a cost-effective option. The risks and costs of needing to restart OPV use change the economics of the polio endgame, although the time horizon used for modeling impacts the overall economic results. National health leaders will want to consider the expected health and economic net benefits of their national polio vaccine strategies recognizing that preferred strategies may differ.

Indexed as

Cost-Benefit AnalysisEconomics, MedicalGlobal HealthHealth Care CostsHealth PolicyHumansImmunizationModels, EconomicModels, TheoreticalPoliomyelitisPoliovirusPoliovirus Vaccine, InactivatedPoliovirus Vaccine, OralRiskStochastic ProcessesPoliovirus Vaccine, InactivatedPoliovirus Vaccine, OralDynamic modelingeradicationhealth economicspolio

Identifiers

PMID33590519
PMCPMC7895457
OpenAlexW3130141170

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.