SynthesisSurgery today2021
Corticosteroids in idiopathic granulomatous mastitis: a systematic review and meta-analysis.
Synthesis in Surgery today, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06985537 (Efficacy of Ultrasound Guided Intralesional Steroid Injection in Idiopathic Granulomatous Mastitis), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Ultrasound Guided Intralesional Steroid Injection in Idiopathic Granulomatous Mastitis (IGM)
Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Therapeutic strategies for idiopathic granulomatous mastitis: an umbrella review of systematic reviews and meta-analyses.Frontiers in medicine · 2026Pooled it
- Clinical efficacy of different methods for treatment of granulomatous lobular mastitis: A systematic review and network meta-analysis.PloS one · 2025Pooled it
- Treatment modalities for granulomatous mastitis, seeking the most appropriate treatment with the least recurrence rate: a systematic review and meta-analysis.European journal of medical research · 2024Pooled it
- A meta-analysis of idiopathic granulomatous mastitis treatments for remission and recurrence prevention.Frontiers in medicine · 2024Pooled it
- Bioactive Compounds from Kefir and Their Potential Benefits on Health: A Systematic Review and Meta-Analysis.Oxidative medicine and cellular longevity · 2021Pooled it
- An endocrine microbe immunity framework for granulomatous mastitis toward phenotype-oriented interpretation.iScience · 2026Review
- Idiopathic granulomatous mastitis: A scoping review to determine the quality and geography of the evidence base.Breast (Edinburgh, Scotland) · 2026Article
- Article
- Idiopathic Granulomatous Mastitis in a Postmenopausal Woman Mimicking Breast Carcinoma: A Diagnostic Challenge.Cureus · 2026Article
- Article
- Clinical Analysis of Comprehensive Pharmacotherapy Combined With Ultrasound-Guided Precise Lesion Resection Plus Primary Microplasty in the Treatment of Nonpuerperal Mastitis.The breast journal · 2026Article
- Treatment Outcomes of Lobular Granulomatous Mastitis: Impact of Hyperprolactinemia, Diabetes, and Erythema Nodosum-Insights From a 7-Year Cohort Study.The breast journal · 2026Article
- Evaluating the efficacy of topical steroids in idiopathic granulomatous mastitis: a prospective cohort study.Gland surgery · 2025Article
- Idiopathic Granulomatous Mastitis: A Consensus Report on Treatment and Follow-Up Approaches Based on the Turkish Clinical Classification.Breast care (Basel, Switzerland) · 2025Article
- Clinical effect of ultrasound-guided microwave ablation in the treatment of 60 patients with non-puerperal mastitis.BMC women's health · 2025Article
- Article
- Idiopathic Granulomatous Mastitis: Immune-Pathogen Imbalance in a Treatment-Resistant Benign Inflammatory Disease.International journal of women's health · 2025Review
- Article
- Corticosteroid Phobia: A Key Barrier to Treatment in Young Women with Idiopathic Granulomatous Mastitis.International journal of women's health · 2025Article
- Current approaches to diagnosing and treating idiopathic granulomatous mastitis: A summary from in-depth clinician interviews.Heliyon · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic granulomatous mastitis (IGM) is an inflammatory disease of the breasts with an unknown etiology. Corticosteroids are one the primary options for treating this disease, but the results of previous studies concerning their efficacy have been controversial. We, therefore, decided to assess the effectiveness of corticosteroids on IGM using a systematic review and meta-analysis. We conducted a systematic search using MeSH terms and all relevant keywords in PubMed, EMBASE, Cochrane Library and Web of Science until May 21, 2019. Data were analyzed using the Comprehensive Meta-Analysis (CMA) V.2 software program and presented as the event rate, risk ratio (RR) and risk difference (RD). Twelve studies including 559 IGM patients were entered into the meta-analysis. Our analysis showed that the RR and RD of recurrence in the steroid-only group compared with the surgery-only group were 2.99 (95% confidence interval [CI] 0.28-31.33) and 0.14 (95% CI - 0.01-0.30), respectively, showing no statistical significance. The meta-analysis of the steroid-only group and steroid + surgery group showed that the RR of recurrence was 6.13 (95% CI 0.41-81.62) with no significance. However, the meta-analysis of the RD showed that the risk of recurrence in the steroid group was significantly higher than that in the steroids + surgery group (RD: 0.28, 95% CI 0.11-0.44). This meta-analysis showed that managing IGM with only steroids may be less effective than the combination of steroids and surgery. This combination approach may result in a lower rate of recurrence and side effects in these patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.