Evidence map›Paper›PMID 33590273›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Zhu Li, Ziren Kong, Junyi Chen, Jiyuan Li, Nan Li, Zhi Yang, Yu Wang, Zhibo Liu

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03980431 (Safety and Clinical Value of 18Fluorine-labeled Boron Tyrosine PET/CT in Patients With Brain Tumors), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03980431 naunknown statusnot on this map

Safety and Clinical Value of 18Fluorine-labeled Boron Tyrosine PET/CT in Patients With Brain Tumors

TypeinterventionalSponsorPeking Union Medical College HospitalRan2018 to 2021Enrolled50ConditionsBrain TumorArmsFBY PET Examination
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Detailed pharmacokinetic features of a novel bis-boronEuropean journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Review
  4. CD98 Light Chain LAT1 Tracers in PET-CT Diagnosis of Cancer Patients.Anti-cancer agents in medicinal chemistry · 2026
    Review
  5. Article
  6. Review
  7. A bis-boron boramino acid PET tracer for brain tumor diagnosis.European journal of nuclear medicine and molecular imaging · 2024
    Article
  8. A histogram of [EJNMMI research · 2024
    Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Carborane-Containing Folic AcidInternational journal of molecular sciences · 2022
    Article
  14. Recent Advances inPharmaceutics · 2022
    Review
  15. LargerEJNMMI research · 2022
    Article
  16. First-in-human study of anEuropean journal of nuclear medicine and molecular imaging · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Zhu Li *Key laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of nuclear medicine, Peking University Cancer Hospital & Institute, Beijing, 100871, China.
Ziren Kong *Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Junyi Chen *Radiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Jiyuan LiRadiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China.
Nan LiKey laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of nuclear medicine, Peking University Cancer Hospital & Institute, Beijing, 100871, China.
Zhi YangKey laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of nuclear medicine, Peking University Cancer Hospital & Institute, Beijing, 100871, China. pekyz@163.com.
Yu WangDepartment of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. ywang@pumch.cn.
Zhibo LiuRadiochemistry and Radiation Chemistry Key Laboratory of Fundamental Science, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, China. zbliu@pku.edu.cn.ORCID 0000-0002-5587-4165
Peking University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this work, the safety, biodistribution, and radiation dosimetry of large neutral amino acid transporter type-1 (LAT-1) targeting PET tracer

methodsSix healthy volunteers (3 M, 3 F) underwent whole-body PET acquisitions at multiple time points after bolus injection of

results

conclusion

trial registrationclinicaltrials.gov (NCT03980431).

Indexed as

GliomaPositron Emission Tomography Computed TomographyHealthy VolunteersHumansPositron-Emission TomographyRadiometryTissue Distribution18F-FBYBoramino acidGliomaLarge neutral amino acid transporter type-1 (LAT-1)PET/CT

Identifiers

PMID33590273
OpenAlexW3131063595

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.