Evidence map›Paper›PMID 33589818›Full record

ReviewNature reviews. Rheumatology2021

Consensus terminology for preclinical phases of psoriatic arthritis for use in research studies: results from a Delphi consensus study.

Lourdes M Perez-Chada, Rebecca H Haberman, Vinod Chandran, Cheryl F Rosen, Christopher Ritchlin, Lihi Eder, Philip Mease, Soumya Reddy, Alexis Ogdie, Joseph F Merola and 1 more

Open access · hybridAbstract readConsensus StatementReview
In one paragraph

Review in Nature reviews. Rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
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  17. Early psoriatic arthritis: when is the right time to start advanced therapy?Therapeutic advances in musculoskeletal disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 2 countries.

Lourdes M Perez-Chada *Department of Dermatology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.
Rebecca H Haberman *Department of Medicine, Division of Rheumatology, New York University Langone Health, New York, NY, USA.ORCID http://orcid.org/0000-0002-7119-8136
Vinod ChandranDepartment of Medicine, Division of Rheumatology, University of Toronto, Toronto, ON, Canada.
Cheryl F RosenDivision of Dermatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada.
Christopher RitchlinAllergy, Immunology, and Rheumatology Division, University of Rochester Medical School, Rochester, NY, USA.
Lihi EderWomen's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON, Canada.
Philip MeaseSeattle Rheumatology Associates, Swedish Medical Center and Providence St, Joseph Health, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6620-0457
Soumya ReddyDepartment of Medicine, Division of Rheumatology, New York University Langone Health, New York, NY, USA.
Alexis OgdieDepartment of Medicine, Division of Rheumatology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Joseph F Merola *Department of Dermatology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA. JFMerola@BWH.Harvard.edu.
Jose U Scher *Department of Medicine, Division of Rheumatology, New York University Langone Health, New York, NY, USA. jose.scher@nyumc.org.
NYU Langone Health · USBrigham and Women's Hospital · USUniversity of Toronto · CAUniversity Health Network · CAUniversity of Pennsylvania · USUniversity of Rochester · USUniversity of Washington · US

Funding

Employing the gut microbiome to accelerate effective initiation of rheumatoid arthritis therapyR01AR074500 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Renuka Rajendra Nayak, Jose U. Scher · 2019 to 2026
$4.1M
Translational Basic and Clinical Research Training in RheumatologyT32AR069515 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Jill P Buyon, Jose U. Scher · 2017 to 2026
$2.9M
NIAMS NIH HHS R01 AR074500NIAMS NIH HHS T32 AR069515
6 · The paper itself

Abstract

The concept of psoriatic arthritis (PsA) prevention is gaining increased interest owing to the physical limitation, poor quality of life and low remission rates that are achieved with current therapies for PsA. The psoriasis-to-PsA transition offers a unique opportunity to identify individuals at increased risk of developing PsA and to implement preventive strategies. However, identifying individuals at increased risk of developing PsA is challenging as there is no consensus on how this population should be defined. This Consensus Statement puts forward recommended terminology from the Psoriasis and Psoriatic Arthritis Clinics Multicenter Advancement Network (PPACMAN) for defining specific subgroups of individuals during the preclinical and early clinical phases of PsA to be used in research studies. Following a three-round Delphi process, consensus was reached for three terms and definitions: 'increased risk for PsA', 'psoriasis with asymptomatic synovio-entheseal imaging abnormalities' and 'psoriasis with musculoskeletal symptoms not explained by other diagnosis'. These terms and their definitions will enable improved identification and standardization of study populations in clinical research. In the future, as increasing evidence emerges regarding the molecular and clinical features of the psoriasis-to-PsA continuum, these terms and definitions will be further refined and updated.

Indexed as

Arthritis, PsoriaticDelphi TechniqueDrug Evaluation, PreclinicalFemaleHumansMalePersons with DisabilitiesPsoriasisQuality of LifeRisk AssessmentTerminology as Topic

Identifiers

PMID33589818
PMCPMC7997804
OpenAlexW3129490578

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.