Evidence map›Paper›PMID 33588923›Full record

Observational studyItalian journal of pediatrics2021

Inhaled corticosteroids use in childhood respiratory diseases: an italian survey on pediatricians' prescription habits.

Giovanni Cerimoniale, Paolo Becherucci, Maria Carmen Verga, Giuseppe Di Mauro, Luciana Indinnimeo, Alberto Villani, Mariangela Tosca, Gian Luigi Marseglia, Marzia Duse, Paolo Biasci and 6 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Italian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 10 institutions in 2 countries.

Giovanni CerimonialePediatric Primary Care, National Pediatric Health Care System, Rome, Italy. giovanni.cerimoniale@gmail.com.ORCID http://orcid.org/0000-0002-1471-9388
Paolo BecherucciPediatric Primary Care, National Pediatric Health Care System, Rome, Italy.
Maria Carmen VergaPediatric Primary Care, National Pediatric Health Care System, Rome, Italy.
Giuseppe Di MauroPediatric Primary Care, National Pediatric Health Care System, Rome, Italy.
Luciana IndinnimeoPediatric Department, "Sapienza" University, Rome, Italy.
Alberto VillaniSIP (Società Italiana di Pediatria), Rome, Italy.
Mariangela ToscaDepartment of Pediatrics, Pulmonology and Allergy Units, "Giannina Gaslini" Institute, Genoa, Italy.
Gian Luigi MarsegliaSIAIP (Società Italiana di Allergologia ed Immunologia Pediatrica), Milan, Italy.
Marzia DusePediatric Department, "Sapienza" University, Rome, Italy.
Paolo BiasciPediatric Primary Care, National Pediatric Health Care System, Rome, Italy.
Mattia DoriaPediatric Primary Care, National Pediatric Health Care System, Rome, Italy.
Diego PeroniSIP (Società Italiana di Pediatria), Rome, Italy.
Giorgio PiacentiniDepartment of Surgical Sciences, Dentistry, Gynecology and Pediatrics, Pediatric Division, University of Verona, Verona, Italy.
Maria Di CiccoDepartment of Clinical and Experimental Medicine, Section of Pediatrics, University of Pisa, Pisa, Italy.
Gabriella PozzobonDepartment of Pediatric, IRCCS San Raffaele Hospital, Milan, Italy.
Riccardo LubranoPediatrics and Neonatology Unit, "Sapienza" University, Latina, Italy.
Società Italiana di Fisica · ITSapienza University of Rome · ITUniversity of Pisa · ITBambino Gesù Children's Hospital · ITIstituto Giannina Gaslini · ITSocietà Italiana di Medicina Generale · ITSocietà Italiana di Nefrologia · ITUniversity of Pavia · ITUniversity of Verona · ITVita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA national consensus document on inhaled corticosteroids (ICS) use in childhood, produced by the main Italian pediatric scientific societies, has been recently released. The aim of this study was to gather information on the current pediatricians' ICS prescription habits in Italy for the management of the most common pediatric respiratory diseases, namely allergic rhinitis (AR), asthma, preschool wheezing and laryngitis.

methodsFrom the 1st October 2018 to the 31st January 2019 a link to an online questionnaire was sent monthly through a newsletter to the members of the Italian Society of Pediatrics. The questionnaire included 18 items on ICS use in the most common pediatric respiratory diseases. Data collection and reporting was based on STROBE Statement Checklist for cross-sectional studies.

resultsOne thousand-two questionnaires were returned from primary care pediatricians (39.1%), hospital pediatricians (38.7%), private practicers (16.4%), university pediatricians (3.1%) and Pediatrics residents (2.7%). We found a good adherence to the international guidelines on AR, with prevalent use of oral antihistamine (60.6%) in the secretive phenotype and nasal ICS in the obstructive phenotype (64.8%). In asthma exacerbations ICS are not used in 53.4% of cases, but they are used at high dose in 27.9% and at low dose in 18.7% of cases. In intermittent asthma, ICS are not chosen as a daily controller therapy in 54.1% of cases, while they are chosen as a low dose daily therapy in 44.5% of cases (high dose in 1.4%). In children with persistent asthma, ICS are chosen as a daily low dose therapy in 67.4% of cases and as a daily high dose therapy in 31%. In the management of preschool wheezing, when a long-term treatment is needed, ICS are chosen both alone and in association with antileukotrienes in 71.4% of cases. Children affected by recurrent asthma exacerbations and wheezing are closely followed up, in particular by their primary care pediatricians. The preference for certain molecules in the treatment of different respiratory diseases also emerged.

conclusionsPediatricians' ICS prescription habits in Italy should be improved, especially in the management of asthma. Future surveys on a more numerous sample will be useful to analyze differences in prescription habits on the basis of pediatricians' work settings and geographical distribution.

Indexed as

Attitude of Health PersonnelHabitsSurveys and QuestionnairesAdministration, InhalationAdrenal Cortex HormonesAdultChildCross-Sectional StudiesDrug PrescriptionsFemaleHumansItalyMaleMiddle AgedPediatriciansRespiratory Tract DiseasesAdrenal Cortex HormonesAllergic rhinitisAsthmaChildrenInhaled corticosteroidsLaryngitisPreschool wheezing

Identifiers

PMID33588923
PMCPMC7885514
OpenAlexW3131401839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.