Evidence map›Paper›PMID 33588880›Full record

ArticleJournal of neuroinflammation2021

ATP-evoked intracellular Ca

Nicole Piera Palomba, Katiuscia Martinello, Germana Cocozza, Sara Casciato, Addolorata Mascia, Giancarlo Di Gennaro, Roberta Morace, Vincenzo Esposito, Heike Wulff, Cristina Limatola and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of neuroinflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Calcium-Activated Potassium Channel KMolecular neurobiology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Nicole Piera PalombaIRCCS Neuromed, Pozzilli, IS, Italy.
Katiuscia MartinelloIRCCS Neuromed, Pozzilli, IS, Italy. katiuscia.martinello@neuromed.it.ORCID http://orcid.org/0000-0002-0423-5689
Germana CocozzaIRCCS Neuromed, Pozzilli, IS, Italy.
Sara CasciatoIRCCS Neuromed, Pozzilli, IS, Italy.
Addolorata MasciaIRCCS Neuromed, Pozzilli, IS, Italy.
Giancarlo Di GennaroIRCCS Neuromed, Pozzilli, IS, Italy.
Roberta MoraceIRCCS Neuromed, Pozzilli, IS, Italy.
Vincenzo EspositoIRCCS Neuromed, Pozzilli, IS, Italy.
Heike WulffDepartment of Pharmacology, University of California, Davis, CA, USA.
Cristina LimatolaIRCCS Neuromed, Pozzilli, IS, Italy.
Sergio FucileIRCCS Neuromed, Pozzilli, IS, Italy.
Istituto Neurologico Mediterraneo · ITUniversity of California, Davis · US

Funding

Microglial K+ Channels in Ischemic StrokeR01NS100294 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WULFF, HEIKE · 2017 to 2020
$1.3M
Ministero della Salute Ricerca Corrente -Fucile- LimatolaNINDS NIH HHS R01 NS100294
6 · The paper itself

Abstract

backgroundIntracellular Ca

methodsFura-2 based fluorescence microscopy was used to measure [Ca

resultsIn human microglia extracellular ATP evoked [Ca

conclusionsOur study confirms a functional role for K

Indexed as

Adenosine TriphosphateCalciumCell Membrane PermeabilityCells, CulturedDrug Resistant EpilepsyHumansIntermediate-Conductance Calcium-Activated Potassium ChannelsIntracellular FluidLipopolysaccharidesMicrogliaTemporal LobeAdenosine TriphosphateCalciumIntermediate-Conductance Calcium-Activated Potassium ChannelsKCNN4 protein, humanLipopolysaccharidesKCa3.1NeuroinflammationPerforated patchPrimary culturesPurinergic signalingTemporal lobe epilepsy

Identifiers

PMID33588880
PMCPMC7883449
OpenAlexW3132629069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.