ArticleBMC neuroscience2021
Cortical hemodynamics as a function of handgrip strength and cognitive performance: a cross-sectional fNIRS study in younger adults.
Article in BMC neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Effect of isometric handgrip exercise on cognitive function: Current evidence, methodology, and safety considerations.Frontiers in physiology · 2022Pooled it
- iTBS on RDLPFC improves performance of motor imagery: a brain-computer interface study combining EEG and fNIRS.Journal of neuroengineering and rehabilitation · 2025Trial
- Article
- The relationship between muscle strength and working memory in older adults: fNIRS-based evidence.Frontiers in psychology · 2026Article
- Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study.BMC public health · 2025Article
- DiADEM-Dance against Dementia-Effect of a Six-Month Dance Intervention on Physical Fitness in Older Adults with Mild Cognitive Impairment: A Randomized, Controlled Trial.Journal of personalized medicine · 2024Article
- Article
- A Comparison of Immersive vs. Non-Immersive Virtual Reality Exercises for the Upper Limb: A Functional Near-Infrared Spectroscopy Pilot Study with Healthy Participants.Journal of clinical medicine · 2023Article
- Dose-Response of Creatine Supplementation on Cognitive Function in Healthy Young Adults.Brain sciences · 2023Article
- Cerebral Hemodynamic Changes during Unaffected Handgrip Exercises in Stroke Patients: An fNIRS Study.Brain sciences · 2023Article
- Cortical activation of neuromuscular electrical stimulation synchronized mirror neuron rehabilitation strategies: an fNIRS study.Frontiers in neurology · 2023Article
- High vagally mediated resting-state heart rate variability is associated with superior working memory function.Frontiers in neuroscience · 2023Article
- Does muscle strength predict working memory? A cross-sectional fNIRS study in older adults.Frontiers in aging neuroscience · 2023Article
- A Link between Handgrip Strength and Executive Functioning: A Cross-Sectional Study in Older Adults with Mild Cognitive Impairment and Healthy Controls.Healthcare (Basel, Switzerland) · 2022Article
- An Overview on Cognitive Function Enhancement through Physical Exercises.Brain sciences · 2021Review
- Higher Handgrip Strength Is Linked to Better Cognitive Performance in Chinese Adults with Hypertension.Brain sciences · 2021Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is growing evidence for a positive correlation between measures of muscular strength and cognitive abilities. However, the neurophysiological correlates of this relationship are not well understood so far. The aim of this study was to investigate cortical hemodynamics [i.e., changes in concentrations of oxygenated (oxyHb) and deoxygenated hemoglobin (deoxyHb)] as a possible link between measures of muscular strength and cognitive performance.
methodsIn a cohort of younger adults (n = 39, 18-30 years), we assessed (i) handgrip strength by a handhold dynamometer, (ii) short-term working memory performance by using error rates and reaction times in the Sternberg task, and (iii) cortical hemodynamics of the prefrontal cortex (PFC) via functional near-infrared spectroscopy (fNIRS).
resultsWe observed low to moderate negative correlations (r
conclusionThe present study provides evidence for a positive neurobehavioral relationship between cortical hemodynamics and cognitive performance. Our findings further imply that in younger adults higher levels of handgrip strength positively influence cortical hemodynamics although the latter did not necessarily culminate in better cognitive performance. Future research should examine whether the present findings can be generalized to other cohorts (e.g., older adults).
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