Evidence map›Paper›PMID 33588763›Full record

ArticleBMC gastroenterology2021

Patient experience with NER1006 as a bowel preparation for colonoscopy: a prospective, multicenter US survey.

Brooks D Cash, Mary Beth C Moncrief, Michael S Epstein, David M Poppers

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05436054 (A Randomised Controlled Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05436054 phase4recruitingnot on this mapstarted 2022, after this paper: background citation

A Randomised Controlled Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy

TypeinterventionalSponsorAalborg University HospitalRan2022 to 2025Enrolled400ConditionsColon DiseaseArmsPicoprep, Plenvu
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Brooks D CashUniversity of Texas Health Science Center, Houston, USA. brooks.d.cash@uth.tmc.edu.
Mary Beth C MoncriefSynchrony Medical Communications, LLC, West Chester, PA, USA.
Michael S EpsteinInvestigative Clinical Research and Digestive Disorders Associates, Annapolis, MD, USA.
David M PoppersNew York University Langone Health, New York, NY, USA.
Digestive Care (United States) · USNYU Langone Health · USThe University of Texas Health Science Center at Houston · US

Funding

Salix Pharmaceuticals study support, funding for technical editorial assistance
6 · The paper itself

Abstract

backgroundNER1006 (Plenvu

methodsAdults were recruited from 444 US community gastrointestinal practices and provided a kit number for enrollment into an online survey to be completed within 2 weeks. Survey questions evaluated colonoscopy history and prior bowel preparation(s) prescribed, patient experience during NER1006 administration, and patient satisfaction with the bowel preparation process. A 9-point predefined grading scale was used to evaluate ease of NER1006 preparation and consumption (range, 1 "very difficult" to 9 "very easy"); the perceived importance of volume requirement and clear liquid options (range, 1 "not important at all" to 9 "very important"); and patient satisfaction (range, 1 "not satisfied at all" to 9 "very satisfied").

results1630 patients were enrolled, 1606 underwent colonoscopy, and 1598 completed the survey between September 15, 2018 and February 28, 2019. Among 1606 patients who had a colonoscopy, 62.5% were female, and the mean patient age was 54.4 years (range 18-89 years). Most patients (74.7%) did not report a family history of colon cancer, 62.6% had undergone prior colonoscopy, and 64.8% were undergoing colonoscopy for routine colorectal cancer screening. A majority (76.1%) of patients who completed the survey reported that NER1006 was very easy to prepare and take, and 89.9% were very or moderately satisfied with NER1006 overall. Most (97.6%) patients reported consuming all or most of the bowel preparation. Among 1005 patients with previous bowel preparation use, 84.7% indicated that their experience with NER1006 was much better or better (65.3%) or about the same (19.4%) compared with previously used bowel preparations, while only 15.3% rated NER1006 as worse or much worse.

conclusionsIn this first real-world, US multicenter survey, patient-reported experience with NER1006 as a bowel preparation for colonoscopy was favorable and adherence was high. The majority of patients were very or moderately satisfied with the overall experience and found it much better/better than previously used bowel preparations.

trial registrationNot applicable.

Indexed as

CatharticsColonoscopyAdolescentAdultAgedAged, 80 and overFemaleHumansLaxativesMaleMiddle AgedPatient Outcome AssessmentPatient SatisfactionPolyethylene GlycolsProspective StudiesYoung AdultCatharticsLaxativesPolyethylene GlycolsBowel preparationCatharticsNER1006Patient satisfactionPlenvuSurveyTreatment adherence

Identifiers

PMID33588763
PMCPMC7885614
OpenAlexW3129923049

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.