ReviewNeurosurgery2021
Diagnostic Pathology of Tumors of Peripheral Nerve.
Review in Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
88 citing papers in PubMed, 150 citations in OpenAlex.
- Magnetic resonance-assisted neuronavigation for resection of deep pelvic nerve sheath tumors: illustrative cases.Journal of neurosurgery. Case lessons · 2026Article
- Spinal and Paraspinal Malignant Peripheral Nerve Sheath Tumors (MPNSTs): Survival, Local Recurrence, and the Relative Importance of Resection Extent and Margin Status.Global spine journal · 2026Review
- A Hybrid Peripheral Nerve Sheath Tumor (Granular Cell Tumor+Schwannoma) of Cystic Duct Origin, Presenting with Gallbladder Enlargement and Abdominal Pain.Internal medicine (Tokyo, Japan) · 2026Article
- Benign and Malignant Peripheral Nerve Sheath Tumors of the Oral Cavity: Two-Case Series Emphasizing Diagnostic Challenges.Diagnostics (Basel, Switzerland) · 2026Article
- Neuroblastoma-like schwannoma: Case report with histopathologic correlationBiomedica : revista del Instituto Nacional de Salud · 2026Review
- Function-preserving microsurgical resection of a massive sporadic cervicothoracic dumbbell neurofibroma: a case report.Journal of surgical case reports · 2026Article
- Bilateral optic neuritis and multiple nerve sheath tumors in a patient with genetically characterized Ehlers-Danlos syndrome: A rare co-occurrence.Radiology case reports · 2026Article
- Article
- The Effect of Clinical, Radiological and Surgical Factors on Postoperative Complications in Solitary Extremity Schwannomas.Journal of clinical medicine · 2026Article
- Posterior Interosseous Nerve Schwannoma Presenting as a Painless Forearm Mass: A Case Report.Cureus · 2026Article
- Misdiagnosed tuberculous myelitis turned out to be spinal malignant peripheral nerve sheath tumor: a case report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Brachial- and lumbosacral plexus tumours zone system for surgery brain and spine nerve edition.Brain & spine · 2026Article
- Giant malignant peripheral nerve sheath tumor: Illustrative case and surgical technique.Surgical neurology international · 2026Article
- Sclerosing perineurioma of the anterior chest wall in an active Caucasian toddler: a case report.Translational pediatrics · 2025Article
- Diagnostic challenges of the neurofibroma-malignant peripheral nerve sheath tumor spectrum in neurofibromatosis type 1: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Plexiform Schwannoma of the Middle Finger: A Rare Benign Mesenchymal Tumor Presenting as a Chronic Digital Swelling.Cureus · 2025Article
- Recurrent Laryngeal Nerve Schwannoma: A Case Report.Cureus · 2025Article
- Epigenetic Mechanisms in Neurofibromatosis Types 1 and 2.Epigenomes · 2025Review
- From benign neurofibromas to malignant peripheral nerve sheath tumors (MPNST): a gaming among multiple factors.Cellular oncology (Dordrecht, Netherlands) · 2025Review
- New models for MPNST: establishment and comprehensive characterization of two tumor cell lines.Cancer cell international · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
Neoplasms of the peripheral nervous system represent a heterogenous group with a wide spectrum of morphological features and biological potential. They range from benign and curable by complete excision (schwannoma and soft tissue perineurioma) to benign but potentially aggressive at the local level (plexiform neurofibroma) to the highly malignant (malignant peripheral nerve sheath tumors [MPNST]). In this review, we discuss the diagnostic and pathologic features of common peripheral nerve sheath tumors, particularly those that may be encountered in the intracranial compartment or in the spine and paraspinal region. The discussion will cover schwannoma, neurofibroma, atypical neurofibromatous neoplasms of uncertain biological potential, intraneural and soft tissue perineurioma, hybrid nerve sheath tumors, MPNST, and the recently renamed enigmatic tumor, malignant melanotic nerve sheath tumor, formerly referred to as melanotic schwannoma. We also discuss the diagnostic relevance of these neoplasms to specific genetic and familial syndromes of nerve, including neurofibromatosis 1, neurofibromatosis 2, and schwannomatosis. In addition, we discuss updates in our understanding of the molecular alterations that represent key drivers of these neoplasms, including neurofibromatosis type 1 and type 2, SMARCB1, LZTR1, and PRKAR1A loss, as well as the acquisition of CDKN2A/B mutations and alterations in the polycomb repressor complex members (SUZ12 and EED) in the malignant progression to MPNST. In summary, this review covers practical aspects of pathologic diagnosis with updates relevant to neurosurgical practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.