Evidence map›Paper›PMID 33587905›Full record

ArticleArchives of biochemistry and biophysics2021

Spectral deconvolution of redox species in the crotonyl-CoA-dependent NADH:ferredoxin oxidoreductase from Megasphaera elsdenii. A flavin-dependent bifurcating enzyme.

Wayne Vigil, Dimitri Niks, Sophie Franz-Badur, Nilanjan Chowdhury, Wolfgang Buckel, Russ Hille

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of biochemistry and biophysics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Wayne VigilDepartment of Biochemistry, University of California, Riverside, Riverside, CA, 92521, USA.
Dimitri NiksDepartment of Biochemistry, University of California, Riverside, Riverside, CA, 92521, USA.
Sophie Franz-BadurDepartment of Biochemistry, University of California, Riverside, Riverside, CA, 92521, USA.
Nilanjan ChowdhuryMax Planck Institute for Terrestrial Microbiology, Marburg, Germany.
Wolfgang BuckelMax Planck Institute for Terrestrial Microbiology, Marburg, Germany; Fachbereich Biologie and Synmikro, Philipps-Universität, Marburg, Germany.
Russ HilleDepartment of Biochemistry, University of California, Riverside, Riverside, CA, 92521, USA. Electronic address: russ.hille@ucr.edu.
University of California, Riverside · USMax Planck Institute for Terrestrial Microbiology · DEPhilipps University of Marburg · DE

Funding

Mechanistic studies of a bifurcating flavoproteinR01GM135088 · NIGMS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI HILLE, RUSS · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM135088
6 · The paper itself

Abstract

We have undertaken a spectral deconvolution of the three FADs of EtfAB/bcd to the spectral changes seen in the course of reduction, including the spectrally distinct anionic and neutral semiquinone states of electron-transferring and bcd flavins. We also demonstrate that, unlike similar systems, no charge-transfer complex is observed on titration of the reduced M. elsdenii EtfAB with NAD

Indexed as

Acyl Coenzyme ABacterial ProteinsMegasphaera elsdeniiNADNADH, NADPH OxidoreductasesOxidation-ReductionAcyl Coenzyme ABacterial Proteinscrotonyl-coenzyme ANADNADH, NADPH OxidoreductasesElectron bifurcationElectron paramagnetic resonanceEnzyme kineticsFlavoproteinRapid-reaction kineticsSpectral deconvolution

Identifiers

PMID33587905
PMCPMC8040930
OpenAlexW3132159287

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.