Evidence map›Paper›PMID 33587181›Full record

ArticlePflugers Archiv : European journal of physiology2021

Investigation into the difference in mitochondrial-cytosolic calcium coupling between adult cardiomyocyte and hiPSC-CM using a novel multifunctional genetic probe.

Patrick Ernst, Kai Chen, Yawen Tang, Seulhee Kim, Jiashiung Guan, Jin He, Min Xie, Jianyi Jay Zhang, Xiaoguang Margaret Liu, Lufang Zhou

Open access · greenAbstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Patrick ErnstDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Kai ChenDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Yawen TangDepartment of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Seulhee KimDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Jiashiung GuanDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Jin HeDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Min XieDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Jianyi Jay ZhangDepartment of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Xiaoguang Margaret LiuDepartment of Biomedical Engineering, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA.
Lufang ZhouDepartment of Medicine, The University of Alabama at Birmingham, Birmingham, AL, 35294, USA. lfzhou@uab.edu.ORCID http://orcid.org/0000-0002-1321-8442
University of Alabama at Birmingham · US

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Delineate the Pathophysiological Effect of Cardiomyocyte-specific Mitochondrial StressR01HL156581 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHOU, LUFANG · 2021 to 2025
$2.2M
Mitochondria-SR Redox Signaling and Ca2+ Handling in Healthy and Failing HeartsR01HL121206 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ZHOU, LUFANG · 2015 to 2019
$1.8M
Pannexin channels in cardiac arrhythmiasR01HL128044 · NHLBI · VANDERBILT UNIVERSITY · PI KNOLLMANN, BJORN C, ZHOU, LUFANG · 2015 to 2018
$1.5M
American Heart Association-American Stroke Association 18PRE34060188NHLBI NIH HHS R01 HL121206NHLBI NIH HHS R01 HL128044NHLBI NIH HHS R01 HL156581NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsCalciumCalcium SignalingCells, CulturedCytosolGenetic TechniquesHumansInduced Pluripotent Stem CellsMiceMitochondriaMyocytes, CardiacRatsRats, Sprague-DawleySarcoplasmic ReticulumCalciumCa2+ cyclingGenetically encoded Ca2+ probehiPSC-CMMitochondrial network

Identifiers

PMID33587181
PMCPMC8100988
OpenAlexW3130329045

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.