Evidence map›Paper›PMID 33587169›Full record

ArticleMikrochimica acta2021

Electrochemical sensing platform based on covalent organic framework materials and gold nanoparticles for high sensitivity determination of theophylline and caffeine.

Qixia Guan, Hao Guo, Rui Xue, Mingyue Wang, Ning Wu, Yujuan Cao, Xin Zhao, Wu Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
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  5. Determination of VEGFMikrochimica acta · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Qixia GuanKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China.
Hao GuoKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China. haoguo12@126.com.
Rui XueCollege of Chemistry and Chemical Engineering, Provincial Key Laboratory of Gansu Higher Education for City Environmental Pollution Control, Lanzhou City University, Lanzhou, 730070, People's Republic of China.
Mingyue WangKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China.
Ning WuKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China.
Yujuan CaoKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China.
Xin ZhaoKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China.
Wu YangKey Lab of Eco-Environments Related Polymer Materials of MOE, Key Lab of Bioelectrochemistry and Environmental Analysis of Gansu Province, Gansu International Scientific and Technological Cooperation Base of Water-Retention Chemical Functional Materials, College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou, 730070, People's Republic of China. xbfsda123@126.com.ORCID 0000-0003-1599-4071
Northwest Normal University · CNLanzhou University · CN

Funding

National Natural Science Foundation of China 21665024
6 · The paper itself

Abstract

A new covalent organic framework (COF) has been prepared with 1,3,6,8-tetra(4-formyl phenyl) pyrene (TFPPy) and 2,6-diaminopyridine (DP) as building units through a Schiff base reaction by a simple tube oven heating procedure and the structure of the COF has been characterized in detail. The obtained DP-Py COF is employed to fabricate a novel electrochemical sensing platform for sensitive and selective determination of theophylline (TP) and caffeine (CAF) simultaneously through compounding with AuNPs; the peak positions of TP and CAF are 0.95 V and 1.28 V, respectively. The synergistic effect between DP-Py COF and AuNPs effectively enhances the analytical sensitivity for the target analytes. Under the optimized experimental conditions, the electrochemical sensing platform shows a sensitive voltammetric response and wide linear range to both TP and CAF, and the detection limits are 0.19 μM and 0.076 μM (S/N = 3), respectively. This method has been successfully used for the determination of TP and CAF in compound paracetamol capsules and black tea samples. The recovery and relative standard deviations (RSD) of TP are 99.3~101% and 97.6~101% and 1.3~2.0% and 1.3~2.1%, respectively, and the recovery and RSD of CAF are 96.1~102% and 99.4~104% and 2.8~3.9% and 1.7~3.2%, respectively. Compared with traditional detection methods, the constructed sensing platform has better performance and is expected to be widely used also in other real sample analyses.

Indexed as

AcetaminophenCaffeineCapsulesDrug ContaminationElectrochemical TechniquesElectrodesGoldLimit of DetectionMetal NanoparticlesMetal-Organic FrameworksReproducibility of ResultsTeaTheophyllineAcetaminophenCaffeineCapsulesGoldMetal-Organic FrameworksTeaTheophyllineCaffeineCovalent organic frameworks (COFs)Differential pulse voltammetryElectrochemical sensorsGold nanoparticlesTheophylline

Identifiers

PMID33587169
OpenAlexW3132205333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.