Evidence map›Paper›PMID 33586918›Full record

ArticleCancer reports (Hoboken, N.J.)2021

The predictive power of C-reactive protein- lymphocyte ratio for in-hospital mortality after colorectal cancer surgery.

İbrahim Mungan, Erdal Birol Bostancı, Erbil Türksal, Büşra Tezcan, Mehmet Nesim Aktaş, Müçteba Can, Dilek Kazancı, Sema Turan

Abstract read
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

İbrahim MunganDepartment of Intensive Care Unit, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.ORCID 0000-0003-0002-3643
Erdal Birol BostancıDepartment of Gastrointestinal Surgery, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.
Erbil TürksalDepartment of Anesthesiology, Ankara Keçiören Eğitim Ve Araştırma Hastanesi, Ankara, Turkey.
Büşra TezcanDepartment of Intensive Care Unit, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.
Mehmet Nesim AktaşDepartment of Intensive Care Unit, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.
Müçteba CanDepartment of Intensive Care Unit, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.ORCID 0000-0002-8316-5075
Dilek KazancıDepartment of Intensive Care Unit, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.
Sema TuranDepartment of Intensive Care Unit, Ankara Eğitim ve Araştırma Şehir Hastanesi, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relation between immunity, inflammation, and tumor development and progression has been emphasized in colorectal cancer widely and the prognosis is linked to the inflammatory reaction of the host as well as the biological behavior of the tumor.

aimIn this study, we aimed to find out the predictive power of C-reactive protein- lymphocyte ratio (CLR) for in-hospital mortality after colorectal surgery. METHODS AND

resultsA series of 388 CRC patients were enrolled in the present retrospective study which was conducted in a tertiary state Hospital in Ankara, Turkey. In-hospital mortality was the main outcome to evaluate the predictive power of inflammatory markers, while the other outcomes that would be evaluated as separate variables were LOS in hospital and LOS in ICU. In this study, there were 260 males and 128 females, and the mean age was 60.9. The in-hospital mortality rate was 3.4% (n = 13) and age, APACHE II score and Charlson comorbidity index score were related to in-hospital mortality statistically. The mean LOS in the hospital was 13.9 days and LOS in ICU was 4.5 days. The CRP levels and the CLR levels were higher both in the preoperative and postoperative periods in the mortality (+) group and the difference was significant statistically (P = .008/ .002 and .004/ <.001, respectively). CLR in the postoperative period had the best predictive power with AUC: 0.876.

conclusionIn conclusion, within the context of our study there appears to be a relationship between CLR, as measured on day 2 postoperatively, and in-hospital mortality. It is observed to be more effective than NLR, ALC, and CRP.

Indexed as

Hospital MortalityLymphocytesAgedAged, 80 and overColectomyColorectal NeoplasmsC-Reactive ProteinFemaleHumansIntensive Care UnitsLymphocyte CountMaleMiddle AgedPostoperative PeriodPredictive Value of TestsPreoperative PeriodC-Reactive Proteincolorectal cancerinflammatory markerin-hospital mortalitypredictive powersurgery

Identifiers

PMID33586918
PMCPMC8222561

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.