Evidence map›Paper›PMID 33586480›Full record

ArticleClinical child psychology and psychiatry2021

Who should we ask about mental health symptoms in adolescents with CFS/ME? Parent-child agreement on the revised children's anxiety and depression scale.

Teona Serafimova, Maria Loades, Daisy Gaunt, Esther Crawley

Open access · hybridAbstract read
In one paragraph

Article in Clinical child psychology and psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Recent research in myalgic encephalomyelitis/chronic fatigue syndrome: an evidence map.Health technology assessment (Winchester, England) · 2025
    Pooled it
  2. Trial
  3. The Relationship Between Parent and Child Anxiety: Testing the Intergenerational Model of Anxiety in Children Born with a Cleft.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2026
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Teona SerafimovaCentre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0001-7445-9728
Maria LoadesCentre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK.ORCID https://orcid.org/0000-0002-0839-3190
Daisy GauntCentre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK.
Esther CrawleyCentre for Academic Child Health, Bristol Medical School, University of Bristol, Bristol, UK.
University of Bristol · GBRoyal United Hospital · GB

Funding

Department of Health DRF-2016-09-021Department of Health SRF-2013-06-013
6 · The paper itself

Abstract

backgroundOne in three adolescents with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) have mental health problems. Multi-informant perspectives are key to psychological assessment. Understanding parent-child agreement is crucial to accurate diagnosis, particularly where severe fatigue limits self-report.

methodsAgreement on the revised children's anxiety and depression scale (RCADs) was assessed between parents and children with CFS/ME (

resultsDiagnostic thresholds were met more frequently based on child-report. Parent- and child-report had similar sensitivity and specificity on RCADS compared to gold-standard diagnostic interviews. Regression analysis found similar accuracy between both reports. For anxiety diagnoses, odds ratio (OR) for child-report was 1.10 (CI = 1.06-1.14), and 1.10 (CI = 1.05-1.14) for parent-report. For depression, OR for child report was 1.26 (CI = 1.11-1.43), while for parent-report is was 1.25 (CI = 1.10-1.41). For total score, OR for child-report was 1.10 (CI = 1.05-1.13) while OR for parent-report was 1.09 (CI = 1.05-1.13).

conclusionsReasonable agreement was observed between parent- and child-report of mental health symptoms in paediatric CFS/ME. While parent-report can facilitate psychological evaluation in CFS/ME, this is not a substitute for a child's own report.

Indexed as

Fatigue Syndrome, ChronicAdolescentAnxietyChildDepressionHumansMental HealthParent-Child RelationsanxietyChronic fatigue syndromedepressionmyalgic encephalomyelitispaediatric chronic fatigue syndromeparent child agreement

Identifiers

PMID33586480
PMCPMC8172254
OpenAlexW3125673719

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.