ReviewBritish journal of clinical pharmacology2021
Improving anticoagulation in sub-Saharan Africa: What are the challenges and how can we overcome them?
Review in British journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Warfarin-Associated Bleeding and Thromboembolic Events in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Pharmacoepidemiology and drug safety · 2025Pooled it
- Meta-analysis of genome-wide association studies of stable warfarin dose in patients of African ancestry.Blood advances · 2024Pooled it
- Atrial fibrillation among adults hospitalized with heart failure in Southern Ethiopia: prevalence, predictors, and embolic complications.BMC research notes · 2026Article
- Deep vein thrombosis as a public health priority: wHO's agenda for Africa 2030.Frontiers in cardiovascular medicine · 2026Review
- Time in Therapeutic Range in Patients with Venous Thromboembolism on Vitamin K Antagonist in a Moroccan Thrombosis Unit : An Observational Study.TH open : companion journal to thrombosis and haemostasis · 2026Article
- Article
- Establishing a National Deep Vein Thrombosis Network in Ghana: findings from a prospective observational study embedded in a capacity-building initiative.BMJ public health · 2026Article
- Elderly coagulation risk in a globalized world: burden, biomarkers, and management in Africa - a narrative review.Annals of medicine and surgery (2012) · 2025Review
- Review
- Cost-Effectiveness Analysis of Surgical Strategies Versus Medical Management for Rheumatic Heart Disease in Rwanda.Journal of the American Heart Association · 2025Article
- Establishing consensus on the implementation of Anticoagulation Stewardship Program with cardiologists in Pakistan: A Delphi study.PloS one · 2025Article
- Clinico-epidemiological characteristics of cerebral venous sinus thrombosis in Kenya: a retrospective case series.Frontiers in stroke · 2025Article
- A "Bundle of Care" to Improve Anticoagulation Control in Patients Receiving Warfarin in Uganda and South Africa: Protocol for an Implementation Study.JMIR research protocols · 2023Article
- Anticoagulation control, outcomes, and associated factors in long-term-care patients receiving warfarin in Africa: a systematic review.Thrombosis journal · 2022Review
- Challenges of Anticoagulation Management Service and Need of Establishing Pharmacist-Led Anticoagulation Clinic in Tertiary Care Teaching Hospital, Ethiopia: A Qualitative Study.Journal of multidisciplinary healthcare · 2022Article
- A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients.Frontiers in pharmacology · 2022Article
- Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward.Frontiers in cardiovascular medicine · 2022Review
- Ethnic Diversity and Warfarin Pharmacogenomics.Frontiers in pharmacology · 2022Review
- Stable warfarin dose prediction in sub-Saharan African patients: A machine-learning approach and external validation of a clinical dose-initiation algorithm.CPT: pharmacometrics & systems pharmacology · 2022Article
- Improving anticoagulation in sub-Saharan Africa: What are the challenges and how can we overcome them?British journal of clinical pharmacology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients in sub-Saharan Africa generally have poor anticoagulation control. We review the potential reasons for this poor control, as well as the potential solutions. Challenges include the affordability and centralisation of anticoagulation care, problems with access to medicines and international normalised ratio monitoring, the lack of locally validated standardized dosing protocols, and low levels of anticoagulation knowledge among healthcare workers and patients. Increasing numbers of patients will need anticoagulation in the future because of the increasing burden of noncommunicable disease in the region. We propose that locally developed "warfarin care bundles" which address multiple anticoagulation challenges in combination may be the most appropriate solution in this setting currently.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.