Evidence map›Paper›PMID 33586170›Full record

ArticleJPEN. Journal of parenteral and enteral nutrition2021

COVID-19 infection in patients with intestinal failure: UK experience.

P J Allan, T Ambrose, C Mountford, A Bond, C Donnellan, R Boyle, C Calvert, E Cernat, E Clarke, S C Cooper and 18 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JPEN. Journal of parenteral and enteral nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. COVID-19 infection in patients with intestinal failure: UK experience.JPEN. Journal of parenteral and enteral nutrition · 2021
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 2 countries.

P J AllanTranslational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.ORCID 0000-0003-2682-772X
T AmbroseTranslational Gastroenterology Unit, NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.ORCID 0000-0001-9286-7485
C MountfordDepartment of Gastroenterology, Freeman Hospital, Newcastle, UK.
A BondDepartment of Gastroenterology, Royal Liverpool and Broadgreen Hospitals, Liverpool, UK.
C DonnellanSt James' and Leeds Gastroenterology Institute, St James' Hospital, Leeds, UK.
R BoyleDepartment of Biochemistry, Aberdeen Royal Infirmary, Aberdeen, UK.
C CalvertDepartment of Gastroenterology, Royal Devon and Exeter Hospital, Exeter, UK.
E CernatDepartment of Paediatric Gastroenterology, Leeds General Infirmary, Leeds, UK.
E ClarkeDepartment of Gastroenterology, Southampton University Hospital, Southampton, UK.
S C CooperGI Medicine, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.ORCID 0000-0003-3621-4345
S DonnellyLeonard Jones' Intestinal Rehabilitation Unit, St Mark's Hospital, Harrow, UK.
B EvansDepartment of Gastroenterology, Bristol Royal Infirmary, Bristol, UK.
M GlynnCentre for Digestive Diseases, Royal London Hospital, London, UK.
R HewettDepartment of Gastroenterology, University of Wales Hospital, Cardiff, UK.
A S HolohanNutrition, Leicester Royal Infirmary, Leicester, UK.
E F LeitchIntestinal Failure Surgery, Glasgow Royal Infirmary, Glasgow, UK.
J Louis-AugusteDepartment of Gastroenterology, St George's, London, UK.
S MehtaIntestinal Failure Unit, University College London Hospitals, London, UK.
S NaikDepartment of Paediatric Gastroenterology, Royal London Children's Hospital, London, UK.
J NightingaleSt Mark's Hospital, Harrow, London.
G RaffertyDepartment of Gastroenterology, Belfast City Hospital, Belfast, UK.
A RodriguesDepartment of Paediatric Gastroenterology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
L SharkeyIntestinal Failure and Transplant, Cambridge University Hospitals, Cambridge, UK.
M SmallLeonard Jones' Intestinal Rehabilitation Unit, St Mark's Hospital, Harrow, UK.
A TeubnerIntestinal Failure Unit, Salford Royal Hospital, Salford, UK.
A UrsPaediatric Gastroenterology, Sheffield Children's Hospital, Sheffield, UK.ORCID 0000-0002-8776-565X
N WyerIntestinal Failure and Nutrition Support, University Hospitals Coventry and Warwickshire, Coventry, UK.
S LalIntestinal Failure Unit, Salford Royal Hospital, Salford, UK.ORCID 0000-0002-6245-8864
St Mark's Hospital · GBUniversity of Oxford · GBAberdeen Royal Infirmary · GBBristol Royal Infirmary · GBCambridge University Hospitals NHS Foundation Trust · GBFreeman Hospital · GBGlasgow Royal Infirmary · GBLeeds General Infirmary · GBLeicester Royal Infirmary · GBManchester Academic Health Science Centre · GBOxford University Hospitals NHS Trust · GBRoyal Devon and Exeter Hospital · GBRoyal Hospital for Children · GBRoyal Liverpool and Broadgreen University Hospital NHS Trust · GBRoyal London Hospital · GBSalford Royal Hospital · GBSheffield Children's Hospital · GBSouthampton Hospital · USSt George's, University of London · GBSt James's University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe direct effect of the coronavirus disease 2019 (COVID-19) pandemic on patients with intestinal failure (IF) has not been described.

methodsWe conducted a nationwide study of UK IF centers to evaluate the infection rates, presentations, and outcomes in patients with types 2 and 3 IF.

resultsA total of 45 patients with IF contracted COVID-19 between March and August 2020; this included 26 of 2191 (1.2%) home parenteral nutrition (HPN)-dependent adults and 19 of 298 (6.4%) adults hospitalized with type 2 IF. The proportion of patients receiving nursing care for HPN administration was higher in those with community-acquired COVID-19 (66.7%) than the proportion in the entire HPN cohort (26.1%; P < .01). Two HPN-dependent and 1 hospitalized patient with type 2 IF died as a direct consequence of the virus (6.7% of 45 patients with types 2 or 3 infected).

conclusionThis is the first study to describe the outcomes of COVID-19 in a large cohort of patients requiring long-term PN. Methods to reduce hospital and community nosocomial spread would likely be beneficial.

Indexed as

COVID-19Intestinal DiseasesParenteral Nutrition, HomeAdultHumansRetrospective StudiesSARS-CoV-2United KingdomCOVID-19home parenteral nutritionintestinal failureoutcome

Identifiers

PMID33586170
PMCPMC8013499
OpenAlexW3133356320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.