Evidence map›Paper›PMID 33586018›Full record

ArticleActa neurochirurgica2021

Follow-up study of a patient with early onset cerebral amyloid angiopathy following childhood cadaveric dural graft.

Kenji Yoshiki, Genjiro Hirose, Kazuhiko Kumahashi, Yukihiko Kohda, Kazunori Ido, Akihiro Shioya, Kouichi Misaki, Kensaku Kasuga

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In one paragraph

Article in Acta neurochirurgica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Kenji YoshikiDepartment of Neurosurgery, Asanogawa General Hospital, Kanazawa, Japan.
Genjiro HiroseDepartment of Neurology, Asanogawa General Hospital, Naka 83, Kosaka-machi, Kanazawa City, Ishikawa Prefecture, 920-8621, Japan. ghirose@asanogawa-gh.or.jp.
Kazuhiko KumahashiDepartment of Neurosurgery, Asanogawa General Hospital, Kanazawa, Japan.
Yukihiko KohdaDepartment of Neurosurgery, Asanogawa General Hospital, Kanazawa, Japan.
Kazunori IdoDepartment of Rehabilitation Medicine, Asanogawa General Hospital, Kanazawa, Japan.
Akihiro ShioyaDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Kanazawa, Japan.
Kouichi MisakiDepartment of Neurosurgery, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Kensaku KasugaDepartment of Molecular Genetics, Brain Research Institute, Niigata University, Niigata, Japan.
Asanogawa General Hospital · JPKanazawa Medical University · JPKanazawa University · JPNiigata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We retrospectively studied the T2 star (T2*)-weighted magnetic resonance imaging (MRI) of a 40-year-old patient diagnosed with symptomatic early-onset cerebral amyloid angiopathy (CAA), occurring 34 years following childhood neurosurgery using a cadaveric dural patch. Our findings revealed that CAA associated with cadaveric dural transplantation could progress rapidly, sometimes with bilateral bleeding. This microbleed evolution is suggestive of water-soluble amyloid-β transmission via cerebrospinal fluid alongside perivascular drainage pathways with deposition in the cerebral artery walls due to clearance disturbances. Multiple intracerebral hemorrhages associated with CAA with a childhood cadaveric dural graft should be considered a life-threatening medical complication.

Indexed as

Magnetic Resonance ImagingAdultAmyloid beta-PeptidesBrain Tissue TransplantationCadaverCerebral Amyloid AngiopathyDura MaterHumansMalePostoperative ComplicationsAmyloid beta-PeptidesCadaveric dural graftCerebral amyloid angiopathyMultiple microbleedsPrion-like transmissionT2* image

Identifiers

PMID33586018
OpenAlexW3131255544

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.